| Long name: |
PAI-2/SerpinB2 Primary Polyclonal Antibody |
| Also known as: |
PAI-2/SerpinB2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PAI-2/SerpinB2 |
| Specificity: |
This is a highly specific antibody against PAI-2/SerpinB2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAI-2 |
| Gene ID number: |
5055 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
It was first discovered in the placenta, SerpinB2 also inhibits tissue plasminogen activator (t-PA), SerpinB2 is found in saliva, SerpinB2 is made by many cell types, SerpinB2 levels are elevated in serum during pregnancy, The shorter form has a deletion just after the start of the mature protein, The structure of PAI-2 is not terribly similar to PAI-1, although it was lowered in some cancers, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency, and in leukemia, and in the skin, and is found intracellularly as an unglycosylated kDa protein, and secreted as a 60 kDa protein, breast cancer and ovarian cancer, but it is unclear what the relative production and distribution is for the shorter sequence, but with micromolar efficiency, has been reported, however, secreted by gingival fibroblasts, which is an E clade serpin, with a predicted mass of 43, 1 kDa and a pI of 5, 69, A shorter SerpinB2 isoform of 382 amino acids, SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HsT1201, Monocyte Arg serpin, Monocyte Arg-serpin, PAI, PAI 2, PAI-2, PAI2, PAI2A, PAI2_RAT, PLANH2, Placental plasminogen activator inhibitor, Plasminogen activator inhibitor 2, Plasminogen activator inhibitor 2 type A, Serpin peptidase inhibitor clade B ovalbumin member 2, SerpinB2, Serpinb2, Urokinase inhibitor, plasminogen activator inhibitor 2, Serpin B2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAI-2/SerpinB2 |
| Short name: |
PAI-2/SerpinB2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
clade B (ovalbumin), member 2 (Antibody to), PAI-2/serpin peptidase inhibitor |
| Alternative technique: |
antibodies |