| Long name: |
Cy7 Conjugated, DNAJC3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DNAJC3 |
| Specificity: |
This is a highly specific antibody against DNAJC3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
360-410/504 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human p58ipk/DNAJC3 |
| Gene ID number: |
5611 |
| Swiss Prot: |
Q13217 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DNAJC3 is widely expressed and can be found at high levels in the testis and pancreas (expression in cell lines is variable), It also functions as a Co-chaperone of HSPA8/HSC70 and is involved in the unfolded protein response (UPR) during ER stress, It has been reported that this protein stimulates the ATPase activity of HSPA8/HSC70, DNAJC3 is also involved in ativiral defense - it is activated in response to infection by influenza virus through the dissociation of DNAJB1, DNAJC3 may act as an inhibitor of both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2/PKR to catalyze phosphorylation of the EIF2A |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
P58 P58IPK HP58 ERdj6 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
DNAJC3 Conjugated |
| Short name: |
Conjugated, DNAJC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, member 3 (Antibody to), subfamily C, DnaJ (Hsp40) homolog |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNAJC3 and IDBG-43059 and ENSG00000102580 and 5611, Dnajc3 and IDBG-186994 and ENSMUSG00000022136 and 100037258, ERdj6 and HP58 and P58 and P58IPK and PRKRI, Plasma membranes, member 3, misfolded protein binding, subfamily C, this GO :0004860 and protein kinase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005790 and smooth endoplasmic reticulum and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0016020 and membrane and cellular component this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031205 and endoplasmic reticulum Sec complex and cellular component this GO :0044267 and cellular protein metabolic process and biological process this GO :0051087 and chaperone binding and molecular function this GO :0051603 and proteolysis involved in cellular protein catabolic process and biological process this GO :0051607 and defense response to virus and biological process this GO :0051787 and misfolded protein binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004860 : protein kinase inhibitor activity, this GO :0004860 : protein kinase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0051087 : chaperone binding and also this GO :0051787 : misfolded protein binding, this GO :0005515 : protein binding, this GO :0051087 : chaperone binding, this GO :0051787 : misfolded protein binding, 68903 and IDBG-632869 and ENSBTAG00000012065 and 286770, DnaJ (Hsp40) homolog |
| Identity: |
9439 |
| Gene: |
DNAJC3 |
More about : DNAJC3 |
| Long gene name: |
DnaJ heat shock protein family (Hsp40) member C3 |
| Synonyms gene: |
PRKRI |
| Synonyms gene name: |
DnaJ (Hsp40) homolog, member 3 , subfamily C |
| Synonyms name: |
double-stranded RNA-activated protein kinase inhibitor protein kinase inhibitor of 58 kDa endoplasmic reticulum DNA J domain-containing protein 6 , interferon-induced |
| Locus: |
13q32, 1 |
| Discovery year: |
1995-09-20 |
| GenBank acession: |
U28424 |
| Entrez gene record: |
5611 |
| Pubmed identfication: |
7511204 8824806 |
| Classification: |
DNAJ (HSP40) heat shock proteins Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000017227 |