c-Raf(Ser338/Tyr340) Antibody, ALEXA FLUOR 350

Catalog number:	bs-1731R-A350 Buy Now
Price:	368 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	c-Raf(Ser338/Tyr340) Antibody, ALEXA FLUOR 350
Quantity:	0.1ml
Related search:	raf alexa fluor antibody antibodies sertyr phosphorylates ser cascade

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Long name:	ALEXA FLUOR 350 Conjugated, c-Raf(Ser338/Tyr340) Polyclonal Antibody
Also known as:	Anti-c-Raf Ser338/Tyr340 PAb ALEXA FLUOR 350
Category:	Conjugated Primary Antibodies
Conjugated with:	350, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	c-Raf Ser338/Tyr340
Specificity:	This is a highly specific antibody against c-Raf Ser338/Tyr340
Modification:	Phosphorylation
Modification Site:	Ser338/Tyr340
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	310-360/648
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Ser338/Tyr340
Gene ID Number:	5894
Swiss Prot:	P04049
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	ADCY5 and ADCY6, Can promote NF-kB activation and inhibit signal transducers involved in motility (ROCK2), Can protect cells from apoptosis also by translocating to the mitochondria where it binds BCL2 and displaces BAD/Bcl2-antagonist of cell death, Phosphorylates PPP1R12A resulting in inhibition of the phosphatase activity, Phosphorylates TNNT2/cardiac muscle troponin T, Phosphorylates adenylyl cyclases: ADCY2, Plays a role in the oncogenic transformation of epithelial cells via repression of the TJ protein, RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2), Regulates Rho signaling and migration, Restricts caspase activation in response to selected stimuli, The phosphorylated form of RAF1 (on residues Ser-338 and Ser-339, and erythroid differentiation, and is required for normal wound healing, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, apoptosis, apoptosis (MAP3K5/ASK1 and STK3/MST2), by PAK1) phosphorylates BAD/Bcl2-antagonist of cell death at 'Ser-75', differentiation, notably Fas stimulation, occludin (OCLN) by inducing the up-regulation of a transcriptional repressor SNAI2/SLUG, pathogen-mediated macrophage apoptosis, proliferation and angiogenesis (RB1), resulting in their activation, survival and oncogenic transformation, which induces down-regulation of OCLN, Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	343nm/442nm
Synonyms:	CMD1NN, CRAF, Proto-oncogene c-RAF, RAF, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, c-Raf, NS5
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 350, Alexa Fluor
Gene target:	c-Raf(Ser338/Tyr340)
Short name:	c-Raf(Ser338/Tyr340) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 350
Alternative name:	ALEXA FLUOR 350, c-Raf(Ser338/Tyr340) (Antibody to)
Alternative technique:	antibodies

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