| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PSD93 Tyr340 |
| Specificity: |
This antibody reacts specifically with PSD93 (Tyr340) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr340 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human PSD93 around the phosphorylation site of Tyr340 |
| Gene ID: |
1740 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif, Neuronal nitric oxide synthase (nNOS), Other neuronal proteins that share this motif (beta 1 adrenergic receptor, There are two principal modes of interaction between PSD 93 and other proteins, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane, some serotonin receptors, some sodium channel subunits, which lacks the T/SXV motif but which has its own PDZ domain, PSD 93 is believed to participate in the clustering of certain proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PSD-93 PSD93 chapsyn-110 PPP1R58 |
| Also known as: |
PSD93 (Tyr340) Polyclonal Antibody |
| Other name: |
Anti-PSD93 (Tyr340) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PSD93 (Tyr340) |
| Short name: |
Anti-PSD93 (Tyr340) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PSD93 (Tyr340) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
2901 |
| Gene: |
DLG2 |
More about : DLG2 |
| Long gene name: |
discs large MAGUK scaffold protein 2 |
| Synonyms gene name: |
chapsyn-110 (Drosophila) discs, discs, large homolog 2, large homolog 2 (Drosophila) discs large homolog 2 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 58 |
| Locus: |
11q14, 1 |
| Discovery year: |
1997-04-21 |
| GenBank acession: |
U32376 |
| Entrez gene record: |
1740 |
| Pubmed identfication: |
8755482 9806853 |
| RefSeq identity: |
NM_001364 |
| Classification: |
Protein phosphatase 1 regulatory subunits Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000134309 |