| Long name: |
Cy5, 5 Conjugated, CXCR6/BONZO Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CXCR6/BONZO |
| Specificity: |
This is a highly specific antibody against CXCR6/BONZO |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
141-164/342 |
| Subcellular location: |
Transmembrane, Helical |
| Source: |
KLH conjugated synthetic peptide derived from human CXCR6 |
| Gene ID number: |
10663 |
| Swiss Prot: |
O00574 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes, During progression of the infection, HIV1 infection relies upon interaction with a chemokine receptor, SIV also utilizes CCR5 in the early stages of infection, They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR), but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15), the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4), usually chemokine (C-C) receptor 5 (CCR5), Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
TYMSTR STRL33 BONZO CD186 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
CXCR6/BONZO Conjugated |
| Short name: |
Conjugated, CXCR6/BONZO Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, chemokine (C-X-C motif) receptor 6/BONZO (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BONZO and CD186 and STRL33 and TYMSTR, C-X-C chemokine receptor activity, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019079 and viral genome replication and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0015026 : coreceptor activity and also this GO :0016494 : C-X-C chemokine receptor activity, this GO :0015026 : coreceptor activity, this GO :0016494 : C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 6 |
| Identity: |
16647 |
| Gene: |
CXCR6 |
More about : CXCR6 |
| Long gene name: |
C-X-C motif chemokine receptor 6 |
| Synonyms gene name: |
chemokine (C-X-C motif) receptor 6 |
| Locus: |
3p21, 31 |
| Discovery year: |
2002-08-23 |
| GenBank acession: |
AF007545 |
| Entrez gene record: |
10663 |
| Pubmed identfication: |
9166430 9230441 |
| Classification: |
CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133448 |