| Long name: |
Biotin Conjugated, CXCR6/BONZO Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CXCR6/BONZO |
| Specificity: |
This is a highly specific antibody against CXCR6/BONZO |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
141-164/342 |
| Subcellular location: |
Transmembrane, Helical |
| Source: |
KLH conjugated synthetic peptide derived from human CXCR6 |
| Gene ID number: |
10663 |
| Swiss Prot: |
O00574 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes, During progression of the infection, HIV1 infection relies upon interaction with a chemokine receptor, SIV also utilizes CCR5 in the early stages of infection, They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR), but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15), the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4), usually chemokine (C-C) receptor 5 (CCR5), Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
TYMSTR STRL33 BONZO CD186 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CXCR6/BONZO Conjugated |
| Short name: |
Conjugated, CXCR6/BONZO Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, chemokine (C-X-C motif) receptor 6/BONZO (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BONZO and CD186 and STRL33 and TYMSTR, C-X-C chemokine receptor activity, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, Plasma membranes, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0019079 and viral genome replication and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0015026 : coreceptor activity and also this GO :0016494 : C-X-C chemokine receptor activity, this GO :0015026 : coreceptor activity, this GO :0016494 : C-X-C chemokine receptor activity, chemokine (C-X-C motif) receptor 6 |
| Identity: |
16647 |
| Gene: |
CXCR6 |
More about : CXCR6 |
| Long gene name: |
C-X-C motif chemokine receptor 6 |
| Synonyms gene name: |
chemokine (C-X-C motif) receptor 6 |
| Locus: |
3p21, 31 |
| Discovery year: |
2002-08-23 |
| GenBank acession: |
AF007545 |
| Entrez gene record: |
10663 |
| Pubmed identfication: |
9166430 9230441 |
| Classification: |
CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133448 |