| Long name: |
ALEXA FLUOR 647 Conjugated, IFI16 Polyclonal Antibody |
| Also known as: |
Anti-I16 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
I16 |
| Specificity: |
This is a highly specific antibody against I16 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IFI16 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Alternatively spliced transcript variants encoding different isoforms have been found for this gene, It modulates p53 function, The encoded protein contains domains involved in DNA binding, The protein localizes to the nucleoplasm and nucleoli, and inhibits cell growth in the Ras/Raf signaling pathway, and interacts with p53 and retinoblastoma-1, and protein-protein interactions, transcriptional regulation, IFI16 is a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
IFNGIP1 PYHIN2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the IFI16 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
IFI16 |
| Short name: |
IFI16 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, gamma-inducible protein 16 (Antibody to), interferon |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0016020 and membrane and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030099 and myeloid cell differentiation and biological process this GO :0030224 and monocyte differentiation and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0042149 and cellular response to glucose starvation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051607 and defense response to virus and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0072332 and intrinsic apoptotic signaling pathway by p53 class mediator and biological process this GO :0097202 and activation of cysteine-type endopeptidase activity and biological process this GO :2000117 and negative regulation of cysteine-type endopeptidase activity and biological process, IFI16 and IDBG-103852 and ENSG00000163565 and 3428, IFNGIP1 and PYHIN2, gamma-inducible protein 16, nuclei, poly(A) RNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001819 and positive regulation of cytokine production and biological process this GO :0002218 and activation of innate immune response and biological process this GO :0003690 and double-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0003690 : double-stranded DNA binding, this GO :0003690 : double-stranded DNA binding and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0044822 : poly(A) RNA binding, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0044822 : poly(A) RNA binding, interferon |
| Identity: |
5395 |
| Gene: |
IFI16 |
More about : IFI16 |
| Long gene name: |
interferon gamma inducible protein 16 |
| Locus: |
1q23, 1 |
| Discovery year: |
1993-09-29 |
| GenBank acession: |
M63838 |
| Entrez gene record: |
3428 |
| Pubmed identfication: |
1526658 7959953 |
| RefSeq identity: |
NM_005531 |
| Classification: |
Pyrin domain containing Pyrin and HIN domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000037108 |