| Long name: |
ALEXA FLUOR 594 Conjugated, HIC2 Polyclonal Antibody |
| Also known as: |
Anti-HIC2 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HIC2 |
| Specificity: |
This is a highly specific antibody against HIC2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIC2 |
| Gene ID Number: |
23119 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
HIC-2 (hypermethylated in cancer 2) possesses zinc finger motifs that are thought to be important for DNA-binding and also has a BTB/POZ domain at the N-terminus, HIC-2 contains a short amino acid sequence that is thought to interact with CtBP, HIC-2 is also known as Hic-3, HIC-2 is highly expressed in cerebellum and is localized to the nucleus in cells, HIC1-related gene on chromosome 22 or Zinc finger and BTB domain-containing protein 30, The gene sequence associated with HIC-2 is thought to be a target for miRNAs (microRNAs) which are expressed in many cancers, The majority of zinc-finger proteins contain a KrÃ, a transcriptional repressor, and is a 615 amino acid protein that is expressed as two isoforms produced by alternative splicing, as well as for the binding of transcription factors, most of which encompass some form of transcriptional activation or repression, suggesting that HIC-2 could possess tumor suppressor capabilities, thereby recruiting histone modifying proteins, which is thought to be important for protein-protein binding, which is thought to interact with KAP1, ¼, Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, ppel-type DNA binding domain and a KRAB domain |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA1020 HRG22 ZBTB30 ZNF907 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
HIC2 |
| Short name: |
HIC2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, HIC2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18595 |
| Gene: |
HIC2 |
More about : HIC2 |
| Long gene name: |
HIC ZBTB transcriptional repressor 2 |
| Synonyms gene name: |
hypermethylated in cancer 2 |
| Locus: |
22q11, 21 |
| Discovery year: |
2002-04-29 |
| GenBank acession: |
AB028943 |
| Entrez gene record: |
23119 |
| Pubmed identfication: |
11554746 |
| Classification: |
BTB domain containing Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000150781 |