| Long name: |
Biotin Conjugated, HIBCH Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HIBCH |
| Specificity: |
This is a highly specific antibody against HIBCH |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HIBCH |
| Gene ID number: |
26275 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects to this gene result in HIBCH deficiency (HIBCHD), Existing as two alternatively spliced isoforms, HIBCH hydrolyzes HIBYL-CoA, HIBCH is highly expressed in liver and kidney, HIBCHD is characterized by the accumulation of methacrylyl-CoA, Localizing to the mitochondria, Phenotypic symptoms include early deterioration of neurological function, a highly reactive compound that undergoes addition reactions with free sulfhydryl groups, a saline catabolite, an intermediate in the minor pathway involved in the metabolism of proprionate, and Î, delayed motor skill development and hypotonia, known alternatively as deficiency of Î, muscle and brain, the gene encoding HIBCH maps to human chromosome 2q32, with lower levels found in heart, ², ², -hydroxyisobutyryl CoA deacylase or methacrylic aciduria, -hydroxypropionyl-CoA, 2, HIBCH is a 386 amino acid protein belonging to the enoyl-CoA hydratase/isomerase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HIBCH Conjugated |
| Short name: |
Conjugated, HIBCH Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, HIBCH (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4908 |
| Gene: |
HIBCH |
More about : HIBCH |
| Long gene name: |
3-hydroxyisobutyryl-CoA hydrolase |
| Synonyms gene name: |
3-hydroxyisobutyryl-Coenzyme A hydrolase |
| Locus: |
2q32, 2 |
| Discovery year: |
1999-12-07 |
| GenBank acession: |
U66669 |
| Entrez gene record: |
26275 |
| Pubmed identfication: |
8824301 |
| Havana BLAST/BLAT: |
OTTHUMG00000132673 |