| Catalog number: | bs-15458R-Biotin |
|---|---|
| Price: | 456 € |
| Supplier: | fabgen |
| Product name: | Hephaestin Antibody, Biotin Conjugated |
| Quantity: | 100 µg |
| Related search: |
| Long name: | Biotin Conjugated, Hephaestin Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Biotinylated |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Hephaestin |
| Specificity: | This is a highly specific antibody against Hephaestin |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Subcellular location: | Extracellular |
| Source: | KLH conjugated synthetic peptide derived from human Hephaestin |
| Gene ID number: | 9843 |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: | Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Hephaestin, Hephaestin can bind six copper ions per monomer and is regulated by the homeobox transcription factor CDX2, Hephaestin is primarily detected in the intestine, Increased levels of iron leads to an increase in CDX2 expression and thus Hephaestin, It mediates the movement of iron across the basolateral membrane in conjunction with ferroportin 1, This is an important link between iron and copper metabolism in mammalian systems, a copper-dependant ferroxidase protein, as copper deficiency leads to reduced hephaestin and reduced iron absorption resulting in anemia, bone trabecural cells and fibroblasts, breast, but is also expressed in colon, is crucial for iron exiting intestinal enterocytes into the circulation, Hephaestin is a single-pass type I membrane protein that belongs to the multicopper oxidase family of proteins |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: | HEPH, HEPH_HUMAN, Hephaestin, CPL |
| Properties: | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | Hephaestin Conjugated |
| Short name: | Conjugated, Hephaestin Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Biotin |
| Alternative name: | biotinilated coupled, Hephaestin (Antibody to) |
| Alternative technique: | antibodies |
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