| Long name: |
ALEXA FLUOR 594 Conjugated, Hephaestin Polyclonal Antibody |
| Also known as: |
Anti-Hephaestin PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Hephaestin |
| Specificity: |
This is a highly specific antibody against Hephaestin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Hephaestin |
| Gene ID Number: |
9843 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Hephaestin, Hephaestin can bind six copper ions per monomer and is regulated by the homeobox transcription factor CDX2, Hephaestin is primarily detected in the intestine, Increased levels of iron leads to an increase in CDX2 expression and thus Hephaestin, It mediates the movement of iron across the basolateral membrane in conjunction with ferroportin 1, This is an important link between iron and copper metabolism in mammalian systems, a copper-dependant ferroxidase protein, as copper deficiency leads to reduced hephaestin and reduced iron absorption resulting in anemia, bone trabecural cells and fibroblasts, breast, but is also expressed in colon, is crucial for iron exiting intestinal enterocytes into the circulation, Hephaestin is a single-pass type I membrane protein that belongs to the multicopper oxidase family of proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0698 CPL |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
Hephaestin |
| Short name: |
Hephaestin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, Hephaestin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4866 |
| Gene: |
HEPH |
More about : HEPH |
| Long gene name: |
hephaestin |
| Locus: |
Xq12 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
AB014598 |
| Entrez gene record: |
9843 |
| Pubmed identfication: |
9988272 9734811 |
| RefSeq identity: |
NM_138737 |
| Havana BLAST/BLAT: |
OTTHUMG00000021732 |
| Locus Specific Databases: |
Mental Retardation database |