| Catalog number: | bs-1531R-Cy5.5 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | ATF4/CREB-2 Antibody, Cy5.5 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy5, 5 Conjugated, ATF4/CREB-2 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | Cy5, 5, 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ATF4/CREB-2 |
| Specificity: | This is a highly specific antibody against ATF4/CREB-2 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen_range: | 240-290/351 |
| Subcellular location: | Cell membrane, Nucleus, Cytoplasm |
| Source: | KLH conjugated synthetic peptide derived from human ATF4 |
| Gene ID number: | 468 |
| Swiss Prot: | P18848 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Activates transcription of SIRT4, Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes, Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity), In concert with DDIT3/CHOP, It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I, Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4, Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress, a sequence present in many viral and cellular promoters, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA, Transcriptional activator |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 675nm/694nm |
| Synonyms: | TAXREB67 CREB-2 |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: | ATF4/CREB-2 Conjugated |
| Short name: | Conjugated, ATF4/CREB-2 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | 5, Cy5 |
| Alternative name: | cyanine 5, 5 coupled, ATF4/CREB-2 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 786 |
| Gene: | ATF4 | More about : ATF4 |
| Long gene name: | activating transcription factor 4 |
| Synonyms gene: | TXREB |
| Synonyms gene name: | activating transcription factor 4 (tax-responsive enhancer element B67) |
| Synonyms name: | tax-responsive enhancer element B67 |
| Locus: | 22q13, 1 |
| Discovery year: | 1992-06-09 |
| GenBank acession: | D90209 |
| Entrez gene record: | 468 |
| Pubmed identfication: | 1847461 1534408 |
| RefSeq identity: | NM_001675 |
| Classification: | Basic leucine zipper proteins |
| Havana BLAST/BLAT: | OTTHUMG00000151099 |
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