ErbB-3/HER3 Antibody, ALEXA FLUOR 647

Catalog number:	bs-1454R-A647 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	ErbB-3/HER3 Antibody, ALEXA FLUOR 647
Quantity:	100ul
Related search:	alexa fluor gene erbb antibodies receptor synonyms alternative

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Long name:	ALEXA FLUOR 647 Conjugated, ErbB-3/HER3 Polyclonal Antibody
Also known as:	Anti-ErbB-3/HER3 PAb ALEXA FLUOR 647
Category:	Conjugated Primary Antibodies
Conjugated with:	647, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	ErbB-3/HER3
Specificity:	This is a highly specific antibody against ErbB-3/HER3
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	670-720/1342
Subcellular location:	Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ErbB-3
Gene ID Number:	2065
Swiss Prot:	P21860
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Additional splice variants have also been reported but they have not been thoroughly characterized, Alternate transcriptional splice variants encoding different isoforms have been characterized, Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain, Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation, However it does form heterodimers with other EGF receptor family members which do have kinase activity, It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation, One isoform lacks the intermembrane region and is secreted outside the cell, This form acts to modulate the activity of the membrane-bound form, bladder and breast tumors, The ErbB3 gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	650nm/665nm
Synonyms:	HER3
Properties:	ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ErbB-3/HER3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 647, Alexa Fluor
Gene target:	ErbB-3/HER3
Short name:	ErbB-3/HER3 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 647
Alternative name:	ALEXA FLUOR 647, ErbB-3/HER3 (Antibody to)
Alternative technique:	antibodies
Identity:	3431
Gene:	ERBB3 | More about : ERBB3
Long gene name:	erb-b2 receptor tyrosine kinase 3
Synonyms gene:	LCCS2
Synonyms gene name:	lethal congenital contracture syndrome 2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Synonyms name:	human epidermal growth factor receptor 3
Locus:	12q13, 2
Discovery year:	1990-07-15
GenBank acession:	M34309
Entrez gene record:	2065
RefSeq identity:	NM_001982
Classification:	Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT:	OTTHUMG00000170140
Locus Specific Databases:	LRG_996

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