| Long name: |
Cy7 Conjugated, CHMP2A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CHMP2A |
| Specificity: |
This is a highly specific antibody against CHMP2A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
20-50/222 |
| Source: |
KLH conjugated synthetic peptide derived from human CHMP2A |
| Gene ID number: |
27243 |
| Swiss Prot: |
O43633 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
-I, ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released, Involved in HIV-1 p6- and p9-dependent virus release, MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, The ESCRT machinery also functions in topologically equivalent membrane fission events, The MVB pathway appears to require the sequential function of ESCRT-O, lysosomal enzymes and lipids, possibly in conjunction with the AAA ATPase VPS4, such as stimulated growth factor receptors, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses), -II and -III complexes, Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
BC-2 CHMP2 VPS2 VPS2A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
CHMP2A Conjugated |
| Short name: |
CHMP2A Antibody Conjugated |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, CHMP2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30216 |
| Gene: |
CHMP2A |
More about : CHMP2A |
| Long gene name: |
charged multivesicular body protein 2A |
| Synonyms gene name: |
chromatin modifying protein 2A |
| Synonyms name: |
cerevisiae) , putative breast adenocarcinoma marker (32kD) VPS2 homolog A (S |
| Locus: |
19q13, 43 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF042384 |
| Entrez gene record: |
27243 |
| Pubmed identfication: |
15173323 11559748 |
| RefSeq identity: |
NM_014453 |
| Classification: |
Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT: |
OTTHUMG00000183547 |