| Long name: |
ALEXA FLUOR 488 Conjugated, CHMP2A Polyclonal Antibody |
| Also known as: |
Anti-CHMP2A PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CHMP2A |
| Specificity: |
This is a highly specific antibody against CHMP2A |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
20-50/222 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP2A |
| Gene ID Number: |
27243 |
| Swiss Prot: |
O43633 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
-I, ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released, Involved in HIV-1 p6- and p9-dependent virus release, MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, The ESCRT machinery also functions in topologically equivalent membrane fission events, The MVB pathway appears to require the sequential function of ESCRT-O, lysosomal enzymes and lipids, possibly in conjunction with the AAA ATPase VPS4, such as stimulated growth factor receptors, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses), -II and -III complexes, Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
BC-2 CHMP2 VPS2 VPS2A |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CHMP2A Antibody has a very high photo stability, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CHMP2A |
| Short name: |
CHMP2A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CHMP2A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30216 |
| Gene: |
CHMP2A |
More about : CHMP2A |
| Long gene name: |
charged multivesicular body protein 2A |
| Synonyms gene name: |
chromatin modifying protein 2A |
| Synonyms name: |
cerevisiae) , putative breast adenocarcinoma marker (32kD) VPS2 homolog A (S |
| Locus: |
19q13, 43 |
| Discovery year: |
2005-04-04 |
| GenBank acession: |
AF042384 |
| Entrez gene record: |
27243 |
| Pubmed identfication: |
15173323 11559748 |
| RefSeq identity: |
NM_014453 |
| Classification: |
Charged multivesicular body proteins ESCRT-III |
| Havana BLAST/BLAT: |
OTTHUMG00000183547 |