| Long name: |
Cy5 Conjugated, Zonula occludens protein 3 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Zonula occludens protein 3 |
| Specificity: |
This is a highly specific antibody against Zonula occludens protein 3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Zonula occludens protein 3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
In addition, Many of the tight junction-associated proteins are members of the membrane-associated guanylate kinase (MAGUK) family and include occludin, These proteins are thought to have both structural and signaling roles, ZO-1, ZO-1 expression is significantly reduced in many breast cancer lines (8), ZO-1 forms complexes with either ZO-2 or ZO-3 (4), ZO-2 and ZO-3 (1, ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, ZO-2 is not expressed in nonepithelial tissue (2, and are characteristically defined by three protein-protein interaction modules: the PDZ domain, and unlike ZO-1, at tight junction stands, occludin and F-actin, the SH3 domain and the guanylate kinase (GuK) domain (3), these proteins can also associate with claudin, where they provide a linkage between the actin cytoskeleton and the tight junction (5-7), which is also expressed at cell junctions of cardiac myocytes, 2), 3), Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
TJP3, Tight junction protein ZO-3, Tight junction protein ZO3, ZO3, ZO3_HUMAN, Zona occludens protein 3, Zonula occludens protein 3, Tight junction protein 3, ZO-3 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Zonula occludens protein 3 Conjugated |
| Short name: |
Conjugated, Zonula occludens protein 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, Zonula occludens protein 3 (Antibody to) |
| Alternative technique: |
antibodies |