| Long name: |
ALEXA FLUOR 488 Conjugated, Zonula occludens protein 3 Antibody |
| Also known as: |
Anti-Zonula occludens protein 3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Zonula occludens protein 3 |
| Specificity: |
This is a highly specific antibody against Zonula occludens protein 3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Zonula occludens protein 3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In addition, Many of the tight junction-associated proteins are members of the membrane-associated guanylate kinase (MAGUK) family and include occludin, These proteins are thought to have both structural and signaling roles, ZO-1, ZO-1 expression is significantly reduced in many breast cancer lines (8), ZO-1 forms complexes with either ZO-2 or ZO-3 (4), ZO-2 and ZO-3 (1, ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, ZO-2 is not expressed in nonepithelial tissue (2, and are characteristically defined by three protein-protein interaction modules: the PDZ domain, and unlike ZO-1, at tight junction stands, occludin and F-actin, the SH3 domain and the guanylate kinase (GuK) domain (3), these proteins can also associate with claudin, where they provide a linkage between the actin cytoskeleton and the tight junction (5-7), which is also expressed at cell junctions of cardiac myocytes, 2), 3), Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
TJP3, Tight junction protein ZO-3, Tight junction protein ZO3, ZO3, ZO3_HUMAN, Zona occludens protein 3, Zonula occludens protein 3, Tight junction protein 3, ZO-3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Zonula occludens protein 3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Zonula occludens protein 3 |
| Short name: |
Zonula occludens protein 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Zonula occludens protein 3 (Antibody to) |
| Alternative technique: |
antibodies |