| Catalog number: | bs-13705R-Cy3 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | ROBLD3 Antibody, Cy3 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy3 Conjugated, ROBLD3 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | cy3 conjugation kit |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | ROBLD3 |
| Specificity: | This is a highly specific antibody against ROBLD3 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human ROBLD3 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 512, 550nm/570, 615nm |
| Synonyms: | MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2 |
| Properties: | 1 of the ROBLD3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | ROBLD3 Conjugated |
| Short name: | Conjugated, ROBLD3 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy3 |
| Alternative name: | cyanine 3 coupled, ROBLD3 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 29796 |
| Gene: | LAMTOR2 | More about : LAMTOR2 |
| Long gene name: | MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor |
| Synonyms gene: | ROBLD3 |
| Synonyms gene name: | roadblock domain containing 3 |
| Synonyms name: | mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein |
| Locus: | 1q22 |
| Discovery year: | 2008-09-16 |
| GenBank acession: | BC024190 |
| Entrez gene record: | 28956 |
| Pubmed identfication: | 11042152 |
| RefSeq identity: | NM_014017 |
| Classification: | Ragulator complex |
| Havana BLAST/BLAT: | OTTHUMG00000017462 |
| Locus Specific Databases: | MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81 |
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