| Long name: |
ALEXA FLUOR 647 Conjugated, ROBLD3 Polyclonal Antibody |
| Also known as: |
Anti-ROBLD3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ROBLD3 |
| Specificity: |
This is a highly specific antibody against ROBLD3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ROBLD3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ROBLD3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ROBLD3 |
| Short name: |
ROBLD3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, ROBLD3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29796 |
| Gene: |
LAMTOR2 |
More about : LAMTOR2 |
| Long gene name: |
MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor |
| Synonyms gene: |
ROBLD3 |
| Synonyms gene name: |
roadblock domain containing 3 |
| Synonyms name: |
mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein |
| Locus: |
1q22 |
| Discovery year: |
2008-09-16 |
| GenBank acession: |
BC024190 |
| Entrez gene record: |
28956 |
| Pubmed identfication: |
11042152 |
| RefSeq identity: |
NM_014017 |
| Classification: |
Ragulator complex |
| Havana BLAST/BLAT: |
OTTHUMG00000017462 |
| Locus Specific Databases: |
MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81 |