| Long name: |
ALEXA FLUOR 488 Conjugated, ROBLD3 Polyclonal Antibody |
| Also known as: |
Anti-ROBLD3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ROBLD3 |
| Specificity: |
This is a highly specific antibody against ROBLD3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ROBLD3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ROBLD3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
ROBLD3 |
| Short name: |
ROBLD3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, ROBLD3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29796 |
| Gene: |
LAMTOR2 |
More about : LAMTOR2 |
| Long gene name: |
MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor |
| Synonyms gene: |
ROBLD3 |
| Synonyms gene name: |
roadblock domain containing 3 |
| Synonyms name: |
mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein |
| Locus: |
1q22 |
| Discovery year: |
2008-09-16 |
| GenBank acession: |
BC024190 |
| Entrez gene record: |
28956 |
| Pubmed identfication: |
11042152 |
| RefSeq identity: |
NM_014017 |
| Classification: |
Ragulator complex |
| Havana BLAST/BLAT: |
OTTHUMG00000017462 |
| Locus Specific Databases: |
MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81 |