| Long name: |
ALEXA FLUOR 488 Conjugated, PARD6G Polyclonal Antibody |
| Also known as: |
Anti-PARD6G PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PARD6G |
| Specificity: |
This is a highly specific antibody against PARD6G |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PARD6G |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
PARD6G contains one OPR domain, PARD6G is found at highest levels in adult and fetal kidney, PARD6G participates in the linking of GTP-bound Rho small GTPases to atypical protein kinase C (PKC) proteins, The PDZ and pseudo-CRIB domains are required for interaction with Rho small GTPases, This assembly is involved in formation of normal tight junctions at epithelial cell-cell contacts, Though widely expressed, Through its complex formation with PARD3G, When atypical PKC and PARD6G are expressed with a constitutively active RAC, one PDZ (DHR) domain and one pseudo-CRIB domain, the proteins colocalize to the membrane ruffles, which are structures that occur at the leading edge of polarized cells during movement, PARD6G (partitioning defective 6 homolog gamma) is a 376 amino acid adaptor protein that is involved in cell polarization and asymmetrical cell division processes |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PAR-6G PAR6gamma |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PARD6G Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PARD6G |
| Short name: |
PARD6G Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, PARD6G (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16076 |
| Gene: |
PARD6G |
More about : PARD6G |
| Long gene name: |
par-6 family cell polarity regulator gamma |
| Synonyms gene name: |
C, elegans) , par-6 (partitioning defective 6, elegans) homolog gamma par-6 partitioning defective 6 homolog gamma (C |
| Locus: |
18q23 |
| Discovery year: |
2001-07-31 |
| Entrez gene record: |
84552 |
| Pubmed identfication: |
11260256 |
| RefSeq identity: |
NM_032510 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132922 |