| Long name: |
PARD6G Primary Polyclonal Antibody |
| Also known as: |
PARD6G PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PARD6G |
| Specificity: |
This is a highly specific antibody against PARD6G |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PARD6G |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
PARD6G contains one OPR domain, PARD6G is found at highest levels in adult and fetal kidney, PARD6G participates in the linking of GTP-bound Rho small GTPases to atypical protein kinase C (PKC) proteins, The PDZ and pseudo-CRIB domains are required for interaction with Rho small GTPases, This assembly is involved in formation of normal tight junctions at epithelial cell-cell contacts, Though widely expressed, Through its complex formation with PARD3G, When atypical PKC and PARD6G are expressed with a constitutively active RAC, one PDZ (DHR) domain and one pseudo-CRIB domain, the proteins colocalize to the membrane ruffles, which are structures that occur at the leading edge of polarized cells during movement, PARD6G (partitioning defective 6 homolog gamma) is a 376 amino acid adaptor protein that is involved in cell polarization and asymmetrical cell division processes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
PAR 6G, PAR6D, PAR6gamma, Partitioning defective 6 homolog gamma, par 6 partitioning defective 6 homolog gamma, PAR 6 gamma protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PARD6G |
| Short name: |
PARD6G Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PARD6G (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16076 |
| Gene: |
PARD6G |
More about : PARD6G |
| Long gene name: |
par-6 family cell polarity regulator gamma |
| Synonyms gene name: |
C, elegans) , par-6 (partitioning defective 6, elegans) homolog gamma par-6 partitioning defective 6 homolog gamma (C |
| Synonyms: |
PAR-6G PAR6gamma |
| Locus: |
18q23 |
| Discovery year: |
2001-07-31 |
| Entrez gene record: |
84552 |
| Pubmed identfication: |
11260256 |
| RefSeq identity: |
NM_032510 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132922 |