| Long name: |
Biotin Conjugated, PAG1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PAG1 |
| Specificity: |
This is a highly specific antibody against PAG1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
340-390/432 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human PAG1 |
| Gene ID number: |
55824 |
| Swiss Prot: |
Q9NWQ8 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins, May be involved in cell adhesion signaling, Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition, Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PAG CBP |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAG1 Conjugated |
| Short name: |
Conjugated, PAG1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, phosphoprotein associated with glycosphin this GO lipid microdomains 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PAG1 and IDBG-26542 and ENSG00000076641 and 55824, PAG1 and IDBG-644850 and ENSBTAG00000014026 and 614460, Pag1 and IDBG-131044 and ENSMUSG00000027508 and 94212, Plasma membranes, SH2 domain binding, this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0045121 and membrane raft and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0042169 : SH2 domain binding, this GO :0005515 : protein binding, this GO :0042169 : SH2 domain binding, phosphoprotein associated with glycosphin this GO lipid microdomains 1 |
| Identity: |
30043 |
| Gene: |
PAG1 |
More about : PAG1 |
| Long gene name: |
phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| Synonyms gene name: |
phosphoprotein associated with glycosphingolipid microdomains 1 |
| Synonyms name: |
Csk-binding protein transmembrane adaptor protein PAG |
| Locus: |
8q21, 13 |
| Discovery year: |
2005-04-25 |
| GenBank acession: |
AF240634 |
| Entrez gene record: |
55824 |
| Pubmed identfication: |
10790433 |
| RefSeq identity: |
NM_018440 |
| Havana BLAST/BLAT: |
OTTHUMG00000164592 |