| Also known as: |
PAG1 / PAG |
| Other names: |
Csk-binding protein, Csk-binding protein, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, phosphoprotein associated with glycosphingolipid microdomains 1, phosphoprotein associated with glycosphingolipid-enriched microdomains 1, phosphoprotein membrane anchor with glycosphingolipid microdomains 1, transmembrane adapter protein PAG, transmembrane adaptor protein PAG, transmembrane phosphoprotein Cbp, phosphoprotein associated with glycosphingolipid-enriched microdomains 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PAG1 |
| Gene name synonims: |
PAG |
| Other gene names: |
CBP, CBP, PAG, PAG, PAG1, PAG1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b |
| Clone: |
PAG-C1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 46 kD ubiquitously expressed transmembrane adaptor protein present in membrane rafts (glycosphingolipid-enriched microdomains), which however migrates on SDS PAGE gels anomalously as an 80 kD molecule, Recognizes an epitope located in the C-terminal domain of Csk-binding protein (Cbp / PAG) |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, approx, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ PAG-C1] (IgG2b) PAG1 / PAG |
| Short name: |
Mouse Monoclonal [clone PAG-C1] (IgG2b) PAG1 / PAG Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens phosphoprotein associated with glycosphin this GO lipid microdomains 1 / PAG (Antibody to), Mouse monoclonal [clonality PAG-C1] (IgG2b) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PAG1 and IDBG-26542 and ENSG00000076641 and 55824, PAG1 and IDBG-644850 and ENSBTAG00000014026 and 614460, Pag1 and IDBG-131044 and ENSMUSG00000027508 and 94212, Plasma membranes, SH2 domain binding, this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0045121 and membrane raft and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0042169 : SH2 domain binding, this GO :0005515 : protein binding, this GO :0042169 : SH2 domain binding, phosphoprotein associated with glycosphin this GO lipid microdomains 1 |
| Identity: |
30043 |
| Gene: |
PAG1 |
More about : PAG1 |
| Long gene name: |
phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| Synonyms gene name: |
phosphoprotein associated with glycosphingolipid microdomains 1 |
| Synonyms: |
PAG CBP |
| Synonyms name: |
Csk-binding protein transmembrane adaptor protein PAG |
| Locus: |
8q21, 13 |
| Discovery year: |
2005-04-25 |
| GenBank acession: |
AF240634 |
| Entrez gene record: |
55824 |
| Pubmed identfication: |
10790433 |
| RefSeq identity: |
NM_018440 |
| Havana BLAST/BLAT: |
OTTHUMG00000164592 |