| Long name: |
PAG1 Primary Polyclonal Antibody |
| Also known as: |
PAG1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PAG1 |
| Specificity: |
This is a highly specific antibody against PAG1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
340-390/432 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAG1 |
| Gene ID number: |
55824 |
| Swiss Prot: |
Q9NWQ8 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins, May be involved in cell adhesion signaling, Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition, Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Csk-binding protein, PAG, PAG1, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1, Transmembrane adapter protein PAG, Transmembrane phosphoprotein Cbp, CBP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAG1 |
| Short name: |
PAG1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphoprotein associated with glycosphin this GO lipid microdomains 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PAG1 and IDBG-26542 and ENSG00000076641 and 55824, PAG1 and IDBG-644850 and ENSBTAG00000014026 and 614460, Pag1 and IDBG-131044 and ENSMUSG00000027508 and 94212, Plasma membranes, SH2 domain binding, this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0035556 and intracellular signal transduction and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0045121 and membrane raft and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0042169 : SH2 domain binding, this GO :0005515 : protein binding, this GO :0042169 : SH2 domain binding, phosphoprotein associated with glycosphin this GO lipid microdomains 1 |
| Identity: |
30043 |
| Gene: |
PAG1 |
More about : PAG1 |
| Long gene name: |
phosphoprotein membrane anchor with glycosphingolipid microdomains 1 |
| Synonyms gene name: |
phosphoprotein associated with glycosphingolipid microdomains 1 |
| Synonyms: |
PAG CBP |
| Synonyms name: |
Csk-binding protein transmembrane adaptor protein PAG |
| Locus: |
8q21, 13 |
| Discovery year: |
2005-04-25 |
| GenBank acession: |
AF240634 |
| Entrez gene record: |
55824 |
| Pubmed identfication: |
10790433 |
| RefSeq identity: |
NM_018440 |
| Havana BLAST/BLAT: |
OTTHUMG00000164592 |