| Catalog number: | bs-13670R-Cy5 |
|---|---|
| Price: | 2835 € |
| Supplier: | MBS Recombinant Proteins |
| Product name: | TOM1L1 Antibody, Cy5 Conjugated |
| Quantity: | 1000ug |
| Related search: |
| Long name: | Cy5 Conjugated, TOM1L1 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | 5, Cy5 |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | TOM1L1 |
| Specificity: | This is a highly specific antibody against TOM1L1 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human TOM1L1 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | As an interactor and a substrate of Src tyrosine kinases (SFK), Containing a GAT domain and a VHS domain, GAT domain of Tom1L1 binds ubiquitin, GRB2, It is suggested that Tom1L-1 functions as an anti-oncogene by inhibiting the formation of squamous cell carcinomas in skin, PI 3-kinase p85?and various signaling proteins when phosphorylated, Tom1L-1 interacts with Fyn, Tom1L-1 may act as an adapter protein involved in signaling pathways and may promote Fyn activation, Tom1L1 is considered a novel mechanism involved in negative regulation of SFK mitogenic and transforming signals, Tom1L1 modulates SFK partitioning at the plasma membrane and downregulates Src kinases in an endosomal-dependent manner, possibly by disrupting intramolecular SH3-dependent interactions, suggesting participation in the sorting of ubiquitinated proteins into MVBs, Tom1L-1 is a 476 amino acid Golgi apparatus protein belonging to the TOM1 family and is a member of the multivesicular body (MVB) sorting machinery |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 625, 650nm/670nm |
| Synonyms: | SRCASM |
| Properties: | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | TOM1L1 Conjugated |
| Short name: | Conjugated, TOM1L1 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy5 |
| Alternative name: | cyanine 5 coupled, TOM1L1 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 11983 |
| Gene: | TOM1L1 | More about : TOM1L1 |
| Long gene name: | target of myb1 like 1 membrane trafficking protein |
| Synonyms gene name: | target of myb1 (chicken) homolog-like 1 target of myb1 (chicken)-like 1 |
| Locus: | 17q23, 2 |
| Discovery year: | 1998-10-14 |
| GenBank acession: | AJ010071 |
| Entrez gene record: | 10040 |
| Pubmed identfication: | 10329004 15611048 17977829 |
| RefSeq identity: | NM_005486 |
| Havana BLAST/BLAT: | OTTHUMG00000177816 |
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