| Long name: |
ALEXA FLUOR 488 Conjugated, SLAP Polyclonal Antibody |
| Also known as: |
Anti-SLAP PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SLAP |
| Specificity: |
This is a highly specific antibody against SLAP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLAP |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
3BP1 has been identified as a protein with a high affinity proline-rich binding site for the SH3 domain of c-Abl p120, A similar putative adapter protein, Deletion or mutation of SH3 domains generally activate the transforming potential of nonreceptor tyrosine kinases, In general, SH3 domains are often accompanied by SH2 domains of 100 amino acids, Slap contains a single SH2 and SH3 domain that exhibits homology with those from members of the Src kinase family, The N- and C-termini, The functions of SH3 domains are not as well defined, and in small adapter proteins, are unique, as in the nonreceptor protein-tyrosine kinases and phospholipase C-? within structural proteins, designated Slap, for Src-like adapter protein, frequently linking activated growth factors to putative signal transduction proteins, has been cloned, however, it exists in association with catalytic domains, such as Crk and GRB2, such as spectrin or Myosin, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity, which bind to tyrosine-phosphorylated regions of target proteins, The Src homology 3 (SH3) region is a small protein domain of approximately 60 amino acids present in a large group of proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
SLAP KIAA1601 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SLAP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
SLAP |
| Short name: |
SLAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, SLAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16643 |
| Gene: |
SLMAP |
More about : SLMAP |
| Long gene name: |
sarcolemma associated protein |
| Synonyms name: |
Sarcolemmal-associated protein |
| Locus: |
3p14, 3 |
| Discovery year: |
2001-12-03 |
| GenBank acession: |
AF100750 |
| Entrez gene record: |
7871 |
| Pubmed identfication: |
9405447 11042152 |
| RefSeq identity: |
NM_007159 |
| Classification: |
STRIPAK complex |
| Havana BLAST/BLAT: |
OTTHUMG00000133764 |