| Long name: |
Adeno-Associated Virus Capsid Protein VP1 Antibody |
| Also known as: |
Adeno-Associated Virus Capsid Protein VP1 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Adeno-Associated Virus Capsid Protein VP1 |
| Specificity: |
AAV3B, AAV4, AAV9, This antibody will recognize many AAV strains, and AAV13, including AAV5, This is a highly specific antibody against Adeno-Associated Virus Capsid Protein VP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
30-80/724 |
| Source: |
KLH conjugated synthetic peptide derived from Adeno-Associated Virus 5 capsid protein VP1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Virus |
| Cross reactive species details: |
AAV5 |
| Background of the target antigen: |
Binding to the host receptor also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, Binds to host cell heparan sulfate and uses host ITGA5-ITGB1 as coreceptor on the cell surface to provide virion attachment to target cell, The capsid encapsulates the genomic ssDNA, This attachment induces virion internalization predominantly through clathrin-dependent endocytosis, VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus, VP2 and VP3 which differ in their N-terminus, about 22 nm in diameter, and consisting of 60 copies of three size variants of the capsid protein VP1, specifically its phospholipase A2-like region and putative nuclear localization signal(s), Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Parvovirus coat protein VP1, capsid protein, capsid protein AAV5, capsid protein [Adeno-associated virus - 5], capsid protein Adeno-associated 5 virus |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Adeno-Associated Virus Capsid Protein VP1 |
| Short name: |
Adeno-Associated Virus Capsid Protein VP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Species: |
Viruses, Virus |
| Alternative name: |
Adeno-Associated Virus Capsid Protein VP1 (Antibody to) |
| Alternative technique: |
antibodies |