| known also as: |
Anti-Rabbit Polyclonal (IgG) to Sheep YWHAE / 14-3-3 Epsilon |
| known also as: |
Rabbit PAb (IgG) to Ovine YWHAE / 14-3-3 Epsilon |
| known also as: |
Lapin Polyclonal (IgG) to Ovinae YWHAE / 14-3-3 Epsilon |
| known also as: |
YWHAE / 14-3-3 Epsilon |
| known also as: |
14-3-3 Epsilon, 14-3-3 epsilon, 14-3-3 protein epsilon, 14-3-3E, KCIP-1, MDCR, MDS, Sheep YWHAE, YWHAE, Anti-YWHAE / 14-3-3 Epsilon Antibody (N-Terminus) IHC-plus |
| Other names: |
14-3-3 epsilon, 14-3-3 protein epsilon, 14-3-3 protein epsilon, N/A, epididymis luminal protein 2, epsilon, epsilon polypeptide, epsilon polypeptide, mitochondrial import stimulation factor L subunit, protein kinase C inhibitor protein-1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, tyrosine 3/tryptophan 5 -monooxygenase activation protein, 14-3-3 protein epsilon |
| Gene name: |
YWHAE |
| Other gene names: |
14-3-3E, 14-3-3E, HEL2, KCIP-1, MDCR, MDS, YWHAE, YWHAE |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Chicken, Human, Mouse, Rabbit, Rat, Sheep <, /b>, Bovine, Mammal (at least 90% immunogen sequence identity), Predicted Reactivity: <, b> |
| Specificity and cross-reactivity: |
14-3-3 epsilon is expressed in all mammals, 14-3-3 epsilon is thought to deactivate heat shock factor 1 in cells recovering from heat shock, During apoptosis, It is a member of the 14-3-3 family which consists of 30 kD proteins that are involved in multiple protein kinase signalling pathways, It is also a potential suicide susceptibility gene, It is deleted in small cell lung cancers disrupting the G(2) checkpoint, May not react with recombinant proteins that are not N-acetylated, Protein interactions with 14-3-3 show distinct preference for its different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein, When bound by ERK, cleavage of 14-3-3 protein by caspase-3 increases the affinity between bad and Bcl-x(L), cytoskeletal structure, intracellular trafficking and targeting, regulation of cell cycle progression, transcription, Recognizes the acetylated N-terminal of 14-3-3 epsilon |
| Form/Appearance: |
0, 09% sodium azide, Serum |
| Storage and shipping: |
Avoid repeated freezing and thawing, or Store productone at -20 degrees Celsius, +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| About: |
2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target: |
PAb YWHAE / 14-3-3 Epsilon |
| Short name: |
PAb (IgG) YWHAE / 14-3-3 Epsilon |
| Technique: |
IgGs, IgG |
| Host: |
Sheep |
| Isotype: |
IgG |
| Species: |
An adult female sheep is referred to as a , Sheep and goats are also used to produce polyclonals, Sheeps, Some epitopes will also recognize goat proteins, The , a , and a younger sheep as a , (Ovis aries) ELISAs are detecting sheep proteins and antigens, Sheep, a male as a , castrated , ewe , lamb, male as a , ram, sheep , wether |
| Alternative name: |
epsilon polypeptide / 14-3-3 Epsilon, polyclonal (Immunoglobulin G) to ovine tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Alternative technique: |
immunoglobulins |
| Alternative to gene target: |
14-3-3E and HEL2 and KCIP-1 and MDCR and MDS, Plasma membranes, YWHAE and IDBG-14629 and ENSG00000108953 and 7531, YWHAE and IDBG-632682 and ENSBTAG00000005664 and 282125, Ywhae and IDBG-200597 and ENSMUSG00000020849 and 22627, epsilon polypeptide, phosphoprotein binding, this GO :0000086 and G2/M transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0001764 and neuron migration and biological process this GO :0003064 and regulation of heart rate by hormone and biological process this GO :0005515 and protein binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0005871 and kinesin complex and cellular component this GO :0006605 and protein targeting and biological process this GO :0006915 and apoptotic process and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021762 and substantia nigra development and biological process this GO :0021766 and hippocampus development and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0023026 and MHC class II protein complex binding and molecular function this GO :0030424 and axon and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0035308 and negative regulation of protein dephosphorylation and biological process this GO :0035329 and hippo signaling and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042470 and melanosome and cellular component this GO :0042826 and histone deacetylase binding and molecular function this GO :0043281 and regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0044325 and ion channel binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050815 and phosphoserine binding and molecular function this GO :0051219 and phosphoprotein binding and molecular function this GO :0060306 and regulation of membrane repolarization and biological process this GO :0061024 and membrane organization and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0086013 and membrane repolarization during cardiac muscle cell action potential and biological process this GO :0086091 and regulation of heart rate by cardiac conduction and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901016 and regulation of potassium ion transmembrane transporter activity and biological process this GO :1902309 and negative regulation of peptidyl-serine dephosphorylation and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0019899 : enzyme binding and also this GO :0019904 : protein domain specific binding and also this GO :0023026 : MHC class II protein complex binding and also this GO :0032403 : protein complex binding and also this GO :0042826 : histone deacetylase binding and also this GO :0044325 : ion channel binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0050815 : phosphoserine binding and also this GO :0051219 : phosphoprotein binding, this GO :0015459 : potassium channel regulator activity, this GO :0019899 : enzyme binding, this GO :0019904 : protein domain specific binding, this GO :0023026 : MHC class II protein complex binding, this GO :0032403 : protein complex binding, this GO :0042826 : histone deacetylase binding, this GO :0044325 : ion channel binding, this GO :0044822 : poly(A) RNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0050815 : phosphoserine binding, this GO :0051219 : phosphoprotein binding, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Identity: |
12854 |
| Gene: |
YWHAQ |
More about : YWHAQ |
| Long gene name: |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
| Synonyms gene name: |
theta , theta polypeptide protein, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein |
| Synonyms: |
HS1 14-3-3 |
| Synonyms name: |
protein tau |
| Locus: |
2p25, 1 |
| Discovery year: |
1999-08-20 |
| GenBank acession: |
AF070556 |
| Entrez gene record: |
10971 |
| Pubmed identfication: |
11080204 |
| RefSeq identity: |
NM_006826 |
| Classification: |
14-3-3 phospho-serine/phospho-threonine binding proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000013848 |