| Category: |
Conjugated Secondary Antibody |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit |
| Target antigen: |
Rat secretory IgA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal antibody |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug/ul |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:500-2000), WB(1:500-2000) |
| Cross reactivity: |
Rat |
| Background of the target antigen: |
IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA, Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces, The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells, bronchial fluids and milk, gastrointestinal secretion, IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer |
| Purification method: |
This antibody has been purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to one year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Properties: |
&beta, ACA ELISA test kits and for diagnostic detection the IgA of Anti-Beta-2 Glycoprotein 1, Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Beta 2GP1 Ab, Beta-2 Glycoprotein 1 Antibodies IgG, Biotin conjugates can be detected by horseradish peroxidase, Examples are EMA, IgM, Immunoglobulin A , More IgA is produced in mucosal linings than all other types of antibody combined, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, also referred to as , and IgAs, (IgA, 2-Glycoprotein 1 Antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Secondary Antibodies they should be stored frozen at - 24°, antibody , immune function , in the , mucous membranes, sIgA) is an , that plays a critical role in |
| Group: |
Polyclonals and antibodies |
| About: |
Rats are used to make rat monoclonal anti mouse antibodies, Rats , The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, There are less rat- than mouse clones however, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Latin name: |
Rattus norvegicus |
| Gene target: |
secretory Conjugated |
| Short name: |
Conjugated, secretory IgA Polyclonal Antibody |
| Technique: |
IgAs, Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, antibody Conjugates, each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
Rat |
| Isotype: |
IgA |
| Label: |
Biotin |
| Species: |
Rats, Rat |
| Alternative name: |
biotinilated coupled, Rat secretory Immunoglobulin A polyclonal (Antibody to) |
| Alternative technique: |
polyclonals |