| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Rat secretory IgA |
| Specificity: |
This antibody reacts specifically with Rat secretory IgA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
Rat secretory IgA |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
IgA deficiency is the most common immunodeficiency that may affect both serum and mucosal produced IgA, Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces, The production is usually local and antigen specific IgA producing B cells can be found in regions under the lamina propria where they mature into dimeric IgA producing plasma cells, bronchial fluids and milk, gastrointestinal secretion, IgA (immunoglobulin A) is a glycosylated protein of 160 kDa and is produced as a monomer or as a J chain linked dimer |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Rat secretory IgA Polyclonal Antibody |
| Other name: |
Anti-Rat secretory IgA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
&beta, ACA ELISA test kits and for diagnostic detection the IgA of Anti-Beta-2 Glycoprotein 1, Beta 2GP1 Ab, Beta-2 Glycoprotein 1 Antibodies IgG, Examples are EMA, IgM, Immunoglobulin A , More IgA is produced in mucosal linings than all other types of antibody combined, also referred to as , and IgAs, (IgA, 2-Glycoprotein 1 Antibodies, For facs or microscopy Alexa 1 conjugate, antibody , immune function , in the , mucous membranes, sIgA) is an , that plays a critical role in |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
Rats are used to make rat monoclonal anti mouse antibodies, Rats , The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, There are less rat- than mouse clones however, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Latin name: |
Rattus norvegicus |
| Gene target: |
secretory |
| Short name: |
Anti- secretory IgA (Polyclonal) Fluor 594 |
| Technique: |
IgAs, Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
Rat |
| Isotype: |
IgA |
| Label: |
ALEXA |
| Species: |
Rats, Rat |
| Alternative name: |
ALEXA Fluor 594, antibody to-Rat secretory Immunoglobulin A (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
44149 |
| Gene: |
SEC1P |
More about : SEC1P |
| Long gene name: |
pseudogene , secretory blood group 1 |
| Locus: |
19q13, 33 |
| Discovery year: |
2012-06-30 |
| Entrez gene record: |
653677 |
| RefSeq identity: |
NR_004401 |
| Havana BLAST/BLAT: |
OTTHUMG00000154617 |