| Also known as: |
RIPK1 / RIP |
| Other names: |
Cell death protein RIP, RIP-1, RIP-1, Receptor-interacting protein 1, Receptor-interacting serine/threonine-protein kinase 1, Serine/threonine-protein kinase RIP, cell death protein RIP, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor interacting protein, receptor-interacting protein 1, receptor-interacting serine/threonine-protein kinase 1, serine/threonine-protein kinase RIP, receptor-interacting serine/threonine-protein kinase 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
RIPK1 |
| Gene name synonims: |
RIP |
| Other gene names: |
RIP, RIP, RIP-1, RIP1, RIP1, RIPK1, RIPK1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2b, k |
| Clone: |
7H10 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Ammonium sulfate precipitation |
| Form/Appearance: |
0, 0, Sourced in Ascites, and 50% glycerol, 01% BSA, 03% sodium azide, 15M NaCl, HEPES with 0 |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 7H10] (IgG2b, k) RIPK1 / RIP |
| Short name: |
Mouse Monoclonal [clone 7H10] (IgG2b, k) RIPK1 / RIP Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2b |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens receptor (TNFRSF)-interacting serine-threonine kinase 1 / RIP (Antibody to), Mouse monoclonal [clonality 7H10] (IgG2b, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Plasma membranes, RIP and RIP1, RIPK1 and IDBG-57326 and ENSG00000137275 and 8737, RIPK1 and IDBG-636679 and ENSBTAG00000006378 and 504727, Ripk1 and IDBG-143710 and ENSMUSG00000021408 and 19766, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005123 and death receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005123 : death receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005123 : death receptor binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0031625 : ubiquitin protein ligase binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, this GO :0070513 : death domain binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding and also this GO :0070513 : death domain binding, transferring phosphorus-containing groups and molecular function this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0036289 and peptidyl-serine autophosphorylation and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043068 and positive regulation of programmed cell death and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044257 and cellular protein catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051347 and positive regulation of transferase activity and biological process this GO :0060545 and positive regulation of necroptotic process and biological process this GO :0070231 and T cell apoptotic process and biological process this GO :0070266 and necroptotic process and biological process this GO :0070513 and death domain binding and molecular function this GO :0070926 and regulation of ATP:ADP antiporter activity and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component this GO :0097343 and ripoptosome assembly and biological process this GO :0097527 and necroptotic signaling pathway and biological process this GO :1901026 and ripoptosome assembly involved in necroptotic process and biological process this GO :1990000 and amyloid fibril formation and biological process this GO :2000377 and regulation of reactive oxygen species metabolic process and biological process this GO :2000379 and positive regulation of reactive oxygen species metabolic process and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| Identity: |
10019 |
| Gene: |
RIPK1 |
More about : RIPK1 |
| Long gene name: |
receptor interacting serine/threonine kinase 1 |
| Synonyms gene name: |
receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| Synonyms: |
RIP |
| Synonyms name: |
receptor-interacting protein kinase 1 |
| Locus: |
6p25, 2 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
U25994 |
| Entrez gene record: |
8737 |
| Pubmed identfication: |
7538908 8612133 |
| RefSeq identity: |
NM_003804 |
| Classification: |
Ripoptosome |
| Havana BLAST/BLAT: |
OTTHUMG00000014134 |