| Long name: |
ALEXA FLUOR 350 Conjugated, RAPGEF5/Repac Polyclonal Antibody |
| Also known as: |
Anti-RAPGEF5/Repac PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RAPGEF5/Repac |
| Specificity: |
This is a highly specific antibody against RAPGEF5/Repac |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RAPGEF5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Existing as two alternatively spliced isoforms, Guanine nucleotide exchange factors (GEFs), Repac, The gene that encodes Repac maps to human chromosome 7p15, also known as Rap guanine nucleotide exchange factor 5 (RAPGEF5), is a 580 amino acid protein that is expressed in brain and testis, lung, mouse and rat, pancreas and small intestine, placenta, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation, such as Repac, the Repac gene is conserved in cow, with high expression of this region linking to positive response to erlotinib therapy for those with non-small-cell lung cancer, with weaker expression in heart, 3, Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
KIAA0277 GFR MR-GEF |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
RAPGEF5/Repac |
| Short name: |
RAPGEF5/Repac Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, RAPGEF5/Repac (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16862 |
| Gene: |
RAPGEF5 |
More about : RAPGEF5 |
| Long gene name: |
Rap guanine nucleotide exchange factor 5 |
| Synonyms gene name: |
Rap guanine nucleotide exchange factor (GEF) 5 |
| Synonyms name: |
M-Ras-regulated GEF |
| Locus: |
7p15, 3 |
| Discovery year: |
2004-03-01 |
| GenBank acession: |
D87467 |
| Entrez gene record: |
9771 |
| Pubmed identfication: |
9039502 10486569 |
| RefSeq identity: |
NM_012294 |
| Havana BLAST/BLAT: |
OTTHUMG00000152525 |