Gemin 1/SMA Antibody, Cy7 Conjugated

Catalog number:	bs-11561R-Cy7 Buy Now
Price:	332 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Gemin 1/SMA Antibody, Cy7 Conjugated
Quantity:	100ul
Related search:	sma smn antibody gene spinal synonyms protein

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Long name:	Cy7 Conjugated, Gemin 1/SMA Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Cy7
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Gemin 1/SMA
Specificity:	This is a highly specific antibody against Gemin 1/SMA
Modification:	Unmodified
Modification site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from human Gemin 1
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, Nearly identical telomeric and centromeric forms of SMN encode the same protein, SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene, SMN, SMN is expresed in a wide variety of tissues including brain, SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), SMN1, SMNT and BCD541, The SMN complex is found in both the cytoplasm and the nucleus, The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus, The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies), also known as Gemin1, and nuclear SMN mediates recycling of pre-mRNA splicing factors, as well as several spliceosomal snRNP proteins, exists as four isoforms produced by alternative splicing, however, kidney, liver, only mutations in the telomeric form are associated with the disease-state SMA, spinal cord and moderately in skeletal and cardiac muscle, Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	743nm/767nm
Synonyms:	BCD541 SMNT SMA1 SMA2 SMA3 GEMIN1 TDRD16A
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Conjugated:	These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene target:	Gemin 1/SMA Conjugated
Short name:	Conjugated, Gemin 1/SMA Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy7
Alternative name:	cyanine 7 coupled, Gemin 1/SMA (Antibody to)
Alternative technique:	antibodies
Identity:	11117
Gene:	SMN1 | More about : SMN1
Long gene name:	survival of motor neuron 1, telomeric
Synonyms gene:	SMA@ SMA
Synonyms gene name:	Kugelberg-Welander disease) , spinal muscular atrophy (Werdnig-Hoffmann disease
Synonyms name:	gemin-1 tudor domain containing 16A
Locus:	5q13, 2
Discovery year:	1996-12-12
GenBank acession:	U18423
Entrez gene record:	6606
Pubmed identfication:	7813012
RefSeq identity:	NM_000344
Classification:	Tudor domain containing
Havana BLAST/BLAT:	OTTHUMG00000099361
Locus Specific Databases:	SMN1 - Spinal Muscular Atrophy (SMA) Leiden Muscular Dystrophy pages ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_676

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• #protein