| Alternative name 1: |
Clone: 4F6, Mab anti-, PTPN22 |
| Alternative name 2: |
Clone: 4F6, Mab antibody-, PTPN22 |
| Alternative name 3: |
Clone: 4F6, Mab antibody-, PTPN22 |
| Alternative name 4: |
anti-PTPN22 Clone: 4F6 |
| Alternative name 5: |
PTPN22 Clone: 4F6 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4F6, PTPN22 |
| Short name: |
Mouse Monoclonal antibody- Clone: 4F6, PTPN22 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4F6, non-receptor classification 22 (lymphoid), protein tyrosine phosphatase |
| Alternative technique: |
murine |
| Alternative to gene target: |
PTPN22 and IDBG-101222 and ENSG00000134242 and 26191, PTPN22 and IDBG-634891 and ENSBTAG00000019617 and, Ptpn22 and IDBG-181952 and ENSMUSG00000027843 and 19260, kinase binding, non-receptor type 22 (lymphoid), nuclei, this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006470 and protein dephosphorylation and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0019900 and kinase binding and molecular function this GO :0030217 and T cell differentiation and biological process this GO :0032817 and regulation of natural killer cell proliferation and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0035644 and phosphoanandamide dephosphorylation and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050855 and regulation of B cell receptor signaling pathway and biological process this GO :0050856 and regulation of T cell receptor signaling pathway and biological process this GO :0050860 and negative regulation of T cell receptor signaling pathway and biological process this GO :0050868 and negative regulation of T cell activation and biological process, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0016791 : phosphatase activity and also this GO :0017124 : SH3 domain binding and also this GO :0019900 : kinase binding, this GO :0005515 : protein binding, this GO :0016791 : phosphatase activity, this GO :0017124 : SH3 domain binding, this GO :0019900 : kinase binding, protein tyrosine phosphatase |
| Identity: |
9652 |
| Gene: |
PTPN22 |
More about : PTPN22 |
| Long gene name: |
non-receptor type 22 , protein tyrosine phosphatase |
| Synonyms gene: |
PTPN8 |
| Synonyms gene name: |
non-receptor type 22 (lymphoid) , non-receptor type 8 protein tyrosine phosphatase, protein tyrosine phosphatase |
| Synonyms: |
Lyp Lyp1 Lyp2 |
| Locus: |
1p13, 2 |
| Discovery year: |
1999-11-26 |
| GenBank acession: |
AF001846 |
| Entrez gene record: |
26191 |
| Pubmed identfication: |
10068674 1373816 |
| RefSeq identity: |
NM_015967 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000011936 |