| Alternative name 1: |
Clone: 3C1, Mab anti-, TIAM2 |
| Alternative name 2: |
Clone: 3C1, Mab antibody-, TIAM2 |
| Alternative name 3: |
Clone: 3C1, Mab antibody-, TIAM2 |
| Alternative name 4: |
anti-TIAM2 Clone: 3C1 |
| Alternative name 5: |
TIAM2 Clone: 3C1 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 3C1, TIAM2 |
| Short name: |
Mouse Monoclonal antibody- Clone: 3C1, TIAM2 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 3C1, T-cellular lymphoma invasion and metastasis 2 |
| Alternative technique: |
murine |
| Alternative to gene target: |
Plasma membranes, TIAM2 and IDBG-635101 and ENSBTAG00000010047 and 100139161, TIAM2 and IDBG-98237 and ENSG00000146426 and 26230, Tiam2 and IDBG-132548 and ENSMUSG00000023800 and 24001, protein binding, this GO :0005057 and receptor signaling protein activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0030027 and lamellipodium and cellular component this GO :0030175 and filopodium and cellular component this GO :0030426 and growth cone and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043087 and regulation of GTPase activity and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0005057 : receptor signaling protein activity, this GO :0005057 : receptor signaling protein activity and also this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005096 : GTPase activator activity and also this GO :0005515 : protein binding, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005096 : GTPase activator activity, this GO :0005515 : protein binding, T-cell lymphoma invasion and metastasis 2 |
| Identity: |
11806 |
| Gene: |
TIAM2 |
More about : TIAM2 |
| Long gene name: |
T-cell lymphoma invasion and metastasis 2 |
| Synonyms: |
STEF |
| Locus: |
6q25, 2-q25, 3 |
| Discovery year: |
1999-12-02 |
| Entrez gene record: |
26230 |
| Pubmed identfication: |
10512681 |
| RefSeq identity: |
NM_012454 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000015880 |