| Alternative name 1: |
Clone: 5B8, Mab anti-, POU4F3 |
| Alternative name 2: |
Clone: 5B8, Mab antibody-, POU4F3 |
| Alternative name 3: |
Clone: 5B8, Mab antibody-, POU4F3 |
| Alternative name 4: |
anti-POU4F3 Clone: 5B8 |
| Alternative name 5: |
POU4F3 Clone: 5B8 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 5B8, POU4F3 |
| Short name: |
Mouse Monoclonal antibody- Clone: 5B8, POU4F3 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 5B8, POU class 4 homeobox 3 |
| Alternative technique: |
murine |
| Alternative to gene target: |
BRN3C and DFNA15, BT, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007601 and visual perception and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0021562 and vestibulocochlear nerve development and biological process this GO :0031290 and retinal ganglion cell axon guidance and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0042491 and auditory receptor cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048675 and axon extension and biological process this GO :0048839 and inner ear development and biological process this GO :0050885 and neuromuscular process controlling balance and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0060113 and inner ear receptor cell differentiation and biological process, POU4F3 and IDBG-52034 and ENSG00000091010 and 5459, Pou4f3 and IDBG-143219 and ENSMUSG00000024497 and 18998, nuclei, sequence-specific DNA binding transcription factor activity, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, 106485 and IDBG-646158 and ENSBTAG00000018817 and 538520, POU class 4 homeobox 3 |
| Identity: |
9220 |
| Gene: |
POU4F3 |
More about : POU4F3 |
| Long gene name: |
POU class 4 homeobox 3 |
| Synonyms gene: |
DFNA15 DFNA52 DFNA42 |
| Synonyms gene name: |
POU domain class 4, autosomal dominant 42 , autosomal dominant 52 deafness, transcription factor 3 deafness |
| Synonyms: |
BRN3C |
| Locus: |
5q32 |
| Discovery year: |
1998-01-07 |
| GenBank acession: |
U10060 |
| Entrez gene record: |
5459 |
| Pubmed identfication: |
9506947 27535032 |
| RefSeq identity: |
NM_002700 |
| Classification: |
POU class homeoboxes and pseudogenes Deafness associated genes |
| Havana BLAST/BLAT: |
OTTHUMG00000129684 |
| Locus Specific Databases: |
Hereditary Hearing Loss Homepage |