| Long name: |
Src (5B8) Monoclonal Antibody |
| Also known as: |
Src (5B8) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Src |
| Specificity: |
This is a highly specific antibody against Src |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
5B8 |
| Concentration: |
4ug/ul |
| Source: |
Recombinant human protein purified from E, coli (His-src) |
| Gene ID number: |
6714 |
| Swiss Prot: |
P12931 |
| Tested Applications: |
WB |
| Recommended dilutions: |
WB (4 ug/ml) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
90&ndash, Blk, Each of these have a common structure consisting of an unique domain at the N-terminal, Fgr, Fyn, Hck, In immume cells, Integrins are major cellular receptor that mediate cell to cell and cell to substratum interactions, Lck, Lyn, One of the two most important regulatory phosphorylation sites in Src is Tyr527, SH2 and tyrosine kinase domains, Src contains a 14-carbon myristoyl group attached to an SH4 domain, Src is expressed ubiquitously, Src plays a role in cell adhesion, Tyrosine 416 is present in the activation loop and its phosphorylation promotes kinase activity, Under basal conditions in vivo, Yes, a protein&ndash, a unique domain, an SH2 domain, an SH2-kinase linker, an SH3 domain, and Yrk, and a C-terminal regulatory segment, and bone resorption, and phosphotyrosine 527 binds intramolecularly with the Src SH2 domain, and platelets, cell morphology and motility, followed by SH3, however the expression level is higher in brain, including integrin signaling pathway, osteoclasts, the Src-family kinases play roles as critical regulators of a large number of intracellular signaling pathways, 95% of Src is phosphorylated at Tyr527, The members of the Src-family kinases are Src, tyrosine kinase domain (the SH1 domain) |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, SRC, SRC1, THC6, c-SRC, p60-Src, pp60c-src, ASV |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
Src (5B8) Monoclonal |
| Short name: |
Src (5B8) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (5B8) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |