| Alternative name 1: |
Clone: 6E3, Mab anti-, PLEK |
| Alternative name 2: |
Clone: 6E3, Mab antibody-, PLEK |
| Alternative name 3: |
Clone: 6E3, Mab antibody-, PLEK |
| Alternative name 4: |
anti-PLEK Clone: 6E3 |
| Alternative name 5: |
PLEK Clone: 6E3 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 6E3, PLEK |
| Short name: |
Mouse Monoclonal antibody- Clone: 6E3, PLEK |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 6E3, pleckstrin |
| Alternative technique: |
murine |
| Alternative to gene target: |
Extracellular, P47, PLEK and IDBG-54586 and ENSG00000115956 and 5341, PLEK and IDBG-635678 and ENSBTAG00000009658 and 518658, Plek and IDBG-151611 and ENSMUSG00000020120 and 56193, phosphatidylinositol-3, this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006904 and vesicle docking involved in exocytosis and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0010572 and positive regulation of platelet activation and biological process this GO :0010920 and negative regulation of inositol phosphate biosynthetic process and biological process this GO :0010925 and positive regulation of inositol-polyphosphate 5-phosphatase activity and biological process this GO :0016020 and membrane and cellular component this GO :0030030 and cell projection organization and biological process this GO :0030168 and platelet activation and biological process this GO :0030836 and positive regulation of actin filament depolymerization and biological process this GO :0030845 and phospholipase C-inhibiting G-protein coupled receptor signaling pathway and biological process this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0031529 and ruffle organization and biological process this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0032233 and positive regulation of actin filament bundle assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0033625 and positive regulation of integrin activation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043325 and phosphatidylinositol-3, this GO :0005080 : protein kinase C binding, this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043325 : phosphatidylinositol-3, this GO :0005515 : protein binding, this GO :0042803 : protein homodimerization activity, this GO :0043325 : phosphatidylinositol-3, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0046488 and phosphatidylinositol metabolic process and biological process this GO :0050849 and negative regulation of calcium-mediated signaling and biological process this GO :0060305 and regulation of cell diameter and biological process this GO :0070493 and thrombin receptor signaling pathway and biological process this GO :0070527 and platelet aggregation and biological process this GO :0070528 and protein kinase C signaling and biological process this GO :0070560 and protein secretion by platelet and biological process, pleckstrin |
| Identity: |
9070 |
| Gene: |
PLEK |
More about : PLEK |
| Long gene name: |
pleckstrin |
| Synonyms: |
P47 |
| Locus: |
2p14 |
| Discovery year: |
1998-04-07 |
| GenBank acession: |
X07743 |
| Entrez gene record: |
5341 |
| Pubmed identfication: |
2897630 12054651 |
| RefSeq identity: |
NM_002664 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129562 |