| Also known as: |
PLEK / Pleckstrin |
| Other names: |
Platelet 47 kDa protein, Pleckstrin, p47, platelet 47 kDa protein, pleckstrin, pleckstrin, pleckstrin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PLEK |
| Other gene names: |
P47, P47, PLEK, p47, PLEK |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a, k |
| Clone: |
6000 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
Sourced in Ascites, pH 7, 2, PBS |
| Storage and shipping: |
We strongly recommend to avoid freeze/thaw cycles in order to keep the activity of the antibody maximally unchanged, the antibody should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ 6E3] (IgG2a, k) PLEK / Pleckstrin |
| Short name: |
Mouse Monoclonal [clone 6E3] (IgG2a, k) PLEK / Pleckstrin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
sapiens pleckstrin / Pleckstrin (Antibody to), Mouse monoclonal [clonality 6E3] (IgG2a, k) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, P47, PLEK and IDBG-54586 and ENSG00000115956 and 5341, PLEK and IDBG-635678 and ENSBTAG00000009658 and 518658, Plek and IDBG-151611 and ENSMUSG00000020120 and 56193, phosphatidylinositol-3, this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006904 and vesicle docking involved in exocytosis and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0010572 and positive regulation of platelet activation and biological process this GO :0010920 and negative regulation of inositol phosphate biosynthetic process and biological process this GO :0010925 and positive regulation of inositol-polyphosphate 5-phosphatase activity and biological process this GO :0016020 and membrane and cellular component this GO :0030030 and cell projection organization and biological process this GO :0030168 and platelet activation and biological process this GO :0030836 and positive regulation of actin filament depolymerization and biological process this GO :0030845 and phospholipase C-inhibiting G-protein coupled receptor signaling pathway and biological process this GO :0030866 and cortical actin cytoskeleton organization and biological process this GO :0031529 and ruffle organization and biological process this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0032233 and positive regulation of actin filament bundle assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0033625 and positive regulation of integrin activation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043325 and phosphatidylinositol-3, this GO :0005080 : protein kinase C binding, this GO :0005080 : protein kinase C binding and also this GO :0005515 : protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043325 : phosphatidylinositol-3, this GO :0005515 : protein binding, this GO :0042803 : protein homodimerization activity, this GO :0043325 : phosphatidylinositol-3, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045744 and negative regulation of G-protein coupled receptor protein signaling pathway and biological process this GO :0046488 and phosphatidylinositol metabolic process and biological process this GO :0050849 and negative regulation of calcium-mediated signaling and biological process this GO :0060305 and regulation of cell diameter and biological process this GO :0070493 and thrombin receptor signaling pathway and biological process this GO :0070527 and platelet aggregation and biological process this GO :0070528 and protein kinase C signaling and biological process this GO :0070560 and protein secretion by platelet and biological process, pleckstrin |
| Identity: |
9070 |
| Gene: |
PLEK |
More about : PLEK |
| Long gene name: |
pleckstrin |
| Synonyms: |
P47 |
| Locus: |
2p14 |
| Discovery year: |
1998-04-07 |
| GenBank acession: |
X07743 |
| Entrez gene record: |
5341 |
| Pubmed identfication: |
2897630 12054651 |
| RefSeq identity: |
NM_002664 |
| Classification: |
Pleckstrin homology domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129562 |