| Alternative name 1: |
Clone: 4E5, Mab anti-, FRZB |
| Alternative name 2: |
Clone: 4E5, Mab antibody-, FRZB |
| Alternative name 3: |
Clone: 4E5, Mab antibody-, FRZB |
| Alternative name 4: |
anti-FRZB Clone: 4E5 |
| Alternative name 5: |
FRZB Clone: 4E5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4E5, FRZB |
| Short name: |
Mouse Monoclonal antibody- Clone: 4E5, FRZB |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4E5, frizzled-related protein |
| Alternative technique: |
murine |
| Alternative to gene target: |
Extracellular, FRE and FRITZ and FRP-3 and FRZB-1 and FRZB-PEN and FRZB1 and FZRB and hFIZ and OS1 and SFRP3 and SRFP3, FRZB and IDBG-639871 and ENSBTAG00000010977 and 281170, FRZB and IDBG-76878 and ENSG00000162998 and 2487, Frzb and IDBG-183775 and ENSMUSG00000027004 and 20378, Wnt-activated receptor activity, this GO :0001501 and skeletal system development and biological process this GO :0001944 and vasculature development and biological process this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007420 and brain development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008406 and this GO nad development and biological process this GO :0010721 and negative regulation of cell development and biological process this GO :0014033 and neural crest cell differentiation and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0017147 and Wnt-protein binding and molecular function this GO :0030165 and PDZ domain binding and molecular function this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0060029 and convergent extension involved in organogenesis and biological process this GO :0060056 and mammary gland involution and biological process this GO :0060429 and epithelium development and biological process this GO :0061037 and negative regulation of cartilage development and biological process this GO :0061053 and somite development and biological process this GO :0070367 and negative regulation of hepatocyte differentiation and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090103 and cochlea morphogenesis and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0017147 : Wnt-protein binding and also this GO :0030165 : PDZ domain binding and also this GO :0042813 : Wnt-activated receptor activity, this GO :0017147 : Wnt-protein binding, this GO :0030165 : PDZ domain binding, this GO :0042813 : Wnt-activated receptor activity, frizzled-related protein |
| Identity: |
3959 |
| Gene: |
FRZB |
More about : FRZB |
| Long gene name: |
frizzled-related protein |
| Synonyms: |
FRZB-PEN FRZB1 SRFP3 FRP-3 SFRP3 FRE FRITZ FRZB-1 FZRB hFIZ |
| Synonyms name: |
secreted frizzled-related protein 3 |
| Locus: |
2q32, 1 |
| Discovery year: |
1998-07-15 |
| GenBank acession: |
U24163 |
| Entrez gene record: |
2487 |
| Pubmed identfication: |
8824257 9118218 |
| RefSeq identity: |
NM_001463 |
| Classification: |
Secreted frizzled-related proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132597 |