| Alternative name 1: |
Clone: 4C1, Mab anti-, RAB27A |
| Alternative name 2: |
Clone: 4C1, Mab antibody-, RAB27A |
| Alternative name 3: |
Clone: 4C1, Mab antibody-, RAB27A |
| Alternative name 4: |
anti-RAB27A Clone: 4C1 |
| Alternative name 5: |
RAB27A Clone: 4C1 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4C1, RAB27A |
| Short name: |
Mouse Monoclonal antibody- Clone: 4C1, RAB27A |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4C1, member RAS oncogene family, RAB27A |
| Alternative technique: |
murine |
| Alternative to gene target: |
GS2 and HsT18676 and RAB27 and RAM, Plasma membranes, RAB27A and IDBG-12971 and ENSG00000069974 and 5873, Rab27a and IDBG-184264 and ENSMUSG00000032202 and 11891, member RAS oncogene family, myosin V binding, this GO :0001750 and photoreceptor outer segment and cellular component this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005764 and lysosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006605 and protein targeting and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006887 and exocytosis and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0016192 and vesicle-mediated transport and biological process this GO :0016324 and apical plasma membrane and cellular component this GO :0019003 and GDP binding and molecular function this GO :0019882 and antigen processing and presentation and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030141 and secretory granule and cellular component this GO :0030318 and melanocyte differentiation and biological process this GO :0030425 and dendrite and cellular component this GO :0030667 and secretory granule membrane and cellular component this GO :0031489 and myosin V binding and molecular function this GO :0032400 and melanosome localization and biological process this GO :0032402 and melanosome transport and biological process this GO :0032585 and multivesicular body membrane and cellular component this GO :0042470 and melanosome and cellular component this GO :0043316 and cytotoxic T cell degranulation and biological process this GO :0043320 and natural killer cell degranulation and biological process this GO :0043473 and pigmentation and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045921 and positive regulation of exocytosis and biological process this GO :0051875 and pigment granule localization and biological process this GO :0051904 and pigment granule transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070382 and exocytic vesicle and cellular component this GO :0071985 and multivesicular body sorting pathway and biological process, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding and also this GO :0019003 : GDP binding and also this GO :0019904 : protein domain specific binding and also this GO :0031489 : myosin V binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, this GO :0019003 : GDP binding, this GO :0019904 : protein domain specific binding, this GO :0031489 : myosin V binding, RAB27A |
| Identity: |
9766 |
| Gene: |
RAB27A |
More about : RAB27A |
| Long gene name: |
RAB27A, member RAS oncogene family |
| Synonyms: |
RAB27 RAM GS2 HsT18676 |
| Locus: |
15q21, 3 |
| Discovery year: |
1996-11-15 |
| GenBank acession: |
U38654 |
| Entrez gene record: |
5873 |
| Pubmed identfication: |
7592656 |
| RefSeq identity: |
NM_004580 NM_183236 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000131959 |
| Locus Specific Databases: |
RAB27Abase: Mutation registry for Griscelli syndrome, type 2 (GS2) Mutations of the Small Nucleotide-binding Protein 27a Gene LRG_96 |