| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RAB27A |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the RAB27A antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This RAB27A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51159 |
| Purity: |
Antigen affinity |
| Description: |
Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified, Mutations in this gene are associated with Griscelli syndrome type 2, Rab family, The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction, The protein encoded by this gene belongs to the small GTPase superfamily |
| Immunogen: |
A portion of amino acids 136-164 from the human protein was used as the immunogen for this RAB27A antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the RAB27A antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RAB27A |
| Short name: |
RAB27A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
member RAS oncogene family (Antibody to), RAB27A |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GS2 and HsT18676 and RAB27 and RAM, Plasma membranes, RAB27A and IDBG-12971 and ENSG00000069974 and 5873, Rab27a and IDBG-184264 and ENSMUSG00000032202 and 11891, member RAS oncogene family, myosin V binding, this GO :0001750 and photoreceptor outer segment and cellular component this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005764 and lysosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006605 and protein targeting and biological process this GO :0006886 and intracellular protein transport and biological process this GO :0006887 and exocytosis and biological process this GO :0006913 and nucleocytoplasmic transport and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0016192 and vesicle-mediated transport and biological process this GO :0016324 and apical plasma membrane and cellular component this GO :0019003 and GDP binding and molecular function this GO :0019882 and antigen processing and presentation and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030141 and secretory granule and cellular component this GO :0030318 and melanocyte differentiation and biological process this GO :0030425 and dendrite and cellular component this GO :0030667 and secretory granule membrane and cellular component this GO :0031489 and myosin V binding and molecular function this GO :0032400 and melanosome localization and biological process this GO :0032402 and melanosome transport and biological process this GO :0032585 and multivesicular body membrane and cellular component this GO :0042470 and melanosome and cellular component this GO :0043316 and cytotoxic T cell degranulation and biological process this GO :0043320 and natural killer cell degranulation and biological process this GO :0043473 and pigmentation and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045921 and positive regulation of exocytosis and biological process this GO :0051875 and pigment granule localization and biological process this GO :0051904 and pigment granule transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070382 and exocytic vesicle and cellular component this GO :0071985 and multivesicular body sorting pathway and biological process, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding and also this GO :0019003 : GDP binding and also this GO :0019904 : protein domain specific binding and also this GO :0031489 : myosin V binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, this GO :0019003 : GDP binding, this GO :0019904 : protein domain specific binding, this GO :0031489 : myosin V binding, RAB27A |
| Identity: |
9766 |
| Gene: |
RAB27A |
More about : RAB27A |
| Long gene name: |
RAB27A, member RAS oncogene family |
| Synonyms: |
RAB27 RAM GS2 HsT18676 |
| Locus: |
15q21, 3 |
| Discovery year: |
1996-11-15 |
| GenBank acession: |
U38654 |
| Entrez gene record: |
5873 |
| Pubmed identfication: |
7592656 |
| RefSeq identity: |
NM_004580 NM_183236 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000131959 |
| Locus Specific Databases: |
RAB27Abase: Mutation registry for Griscelli syndrome, type 2 (GS2) Mutations of the Small Nucleotide-binding Protein 27a Gene LRG_96 |