| Alternative name 1: |
Clone: 3F7-F5, Mab anti-, LCK |
| Alternative name 2: |
Clone: 3F7-F5, Mab antibody-, LCK |
| Alternative name 3: |
Clone: 3F7-F5, Mab antibody-, LCK |
| Alternative name 4: |
anti-LCK Clone: 3F7-F5 |
| Alternative name 5: |
LCK Clone: 3F7-F5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 3F7-F5, LCK |
| Short name: |
Mouse Monoclonal antibody- Clone: 3F7-F5, LCK |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 3F7-coagulation factor V (proaccelerin, labile factor), lymphocyte-specific protein tyrosine kinase |
| Alternative technique: |
murine |
| Alternative to gene target: |
BT, Cell surfaces, Extracellular, F5 and IDBG-104668 and ENSG00000198734 and 2153, F5 and IDBG-202373 and ENSMUSG00000026579 and 14067, FVL and PCCF and RPRGL1 and THPH2, IMD22 and LSK and p56lck and pp58lck and YT16, LCK and IDBG-644592 and ENSBTAG00000012695 and 508890, LCK and IDBG-95667 and ENSG00000182866 and 3932, Lck and IDBG-191117 and ENSMUSG00000000409 and 16818, coagulation factor V (proaccelerin, labile factor), protein binding, this GO :0000242 and pericentriolar material and cellular component this GO :0001772 and immunological synapse and cellular component this GO :0001948 and glycoprotein binding and molecular function this GO :0003823 and antigen binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0004722 and protein serine/threonine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006882 and cellular zinc ion homeostasis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007568 and aging and biological process this GO :0007596 and blood coagulation and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0010038 and response to metal ion and biological process this GO :0010043 and response to zinc ion and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016311 and dephosphorylation and biological process this GO :0016772 and transferase activity, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0003823 : antigen binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0004722 : protein serine/threonine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0016772 : transferase activity, this GO :0002576 and platelet degranulation and biological process this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007155 and cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0008015 and blood circulation and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0031091 and platelet alpha granule and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component, this GO :0003823 : antigen binding, this GO :0004252 : serine-type endopeptidase activity, this GO :0004252 : serine-type endopeptidase activity and also this GO :0005507 : copper ion binding and also this GO :0005515 : protein binding, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0004722 : protein serine/threonine phosphatase activity, this GO :0005507 : copper ion binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0032403 : protein complex binding, this GO :0042169 : SH2 domain binding, this GO :0042609 : CD4 receptor binding, this GO :0042610 : CD8 receptor binding, this GO :0042802 : identical protein binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0051117 : ATPase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0032403 : protein complex binding and also this GO :0042169 : SH2 domain binding and also this GO :0042609 : CD4 receptor binding and also this GO :0042610 : CD8 receptor binding and also this GO :0042802 : identical protein binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding and also this GO :0051117 : ATPase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0030097 and hemopoiesis and biological process this GO :0030139 and endocytic vesicle and cellular component this GO :0030168 and platelet activation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0031295 and T cell costimulation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042493 and response to drug and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042609 and CD4 receptor binding and molecular function this GO :0042610 and CD8 receptor binding and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045588 and positive regulation of gamma-delta T cell differentiation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0050856 and regulation of T cell receptor signaling pathway and biological process this GO :0050862 and positive regulation of T cell receptor signaling pathway and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051117 and ATPase binding and molecular function this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051249 and regulation of lymphocyte activation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070474 and positive regulation of uterine smooth muscle contraction and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, 23666 and IDBG-631746 and ENSBTAG00000017722 and 280687, lymphocyte-specific protein tyrosine kinase |
| Identity: |
6524 |
| Gene: |
LCK |
More about : LCK |
| Long gene name: |
LCK proto-oncogene, Src family tyrosine kinase |
| Synonyms gene name: |
lymphocyte-specific protein tyrosine kinase |
| Locus: |
1p35, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M36881 |
| Entrez gene record: |
3932 |
| Pubmed identfication: |
2787474 |
| RefSeq identity: |
NM_005356 |
| Classification: |
SH2 domain containing Src family tyrosine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000007463 |
| Locus Specific Databases: |
LRG_153 |