| Alternative name 1: |
Clone: 2G10, Mab anti-, HELLS |
| Alternative name 2: |
Clone: 2G10, Mab antibody-, HELLS |
| Alternative name 3: |
Clone: 2G10, Mab antibody-, HELLS |
| Alternative name 4: |
anti-HELLS Clone: 2G10 |
| Alternative name 5: |
HELLS Clone: 2G10 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 2G10, HELLS |
| Short name: |
Mouse Monoclonal antibody- Clone: 2G10, HELLS |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 2G10, lymphoid-specific, helicase |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008152 and metabolic process and biological process this GO :0010216 and maintenance of DNA methylation and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0031508 and centromeric heterochromatin assembly and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046651 and lymphocyte proliferation and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, HELLS and IDBG-637847 and ENSBTAG00000005979 and 540933, HELLS and IDBG-83141 and ENSG00000119969 and 3070, Hells and IDBG-163438 and ENSMUSG00000025001 and 15201, LSH and PASG and SMARCA6, centromeric region and cellular component this GO :0001655 and urogenital system development and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0004386 and helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005721 and centromeric heterochromatin and cellular component this GO :0006306 and DNA methylation and biological process this GO :0006342 and chromatin silencing and biological process this GO :0006346 and methylation-dependent chromatin silencing and biological process this GO :0006351 and transcription, hydrolase activity, lymphoid-specific, nuclei, this GO :0000775 and chromosome, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0004386 : helicase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016787 : hydrolase activity, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0004386 : helicase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016787 : hydrolase activity, helicase |
| Identity: |
4861 |
| Gene: |
HELLS |
More about : HELLS |
| Long gene name: |
helicase, lymphoid-specific |
| Synonyms: |
PASG SMARCA6 LSH Nbla10143 |
| Synonyms name: |
SWI/SNF2-related, actin-dependent regulator of chromatin, matrix-associated, member 6 proliferation-associated SNF2-like protein , subfamily A |
| Locus: |
10q23, 33 |
| Discovery year: |
1998-07-15 |
| GenBank acession: |
AF155827 |
| Entrez gene record: |
3070 |
| Pubmed identfication: |
9878251 10910076 |
| RefSeq identity: |
NM_018063 |
| Classification: |
DNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000018793 |