| Gene info: |
B cells and hepatocytes, IFN beta, IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, IL-6 appears to interact with IL2 in the proliferation of T lymphocytes, IL-6 is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells, IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors, IL17 and downregulated by glucocorticoids IL4, IL6 has also been implicated in regulating adipose mass, In addition, It acts upon a variety of cells including fibroblasts, It is upregulated by IL1, NGF, PDGF, T cells, TGF beta, TNF, TNF alpha, activated T cells, activated monocytes or macrophages and endothelial cells, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response, myeloid progenitor cells, IL-6 is reported to be produced by fibroblasts |
| Gene names: |
B-cell stimulatory factor 2, BSF2, HGF, HSF, IFNB2, IL-6, Interleukin-6, Interleukin 6 |
| Antibodie's label: |
unlabelled serum |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
1, 2-2B11-2G10 |
| Antigen: |
The monoclonal antibody was produced in BALB/c x C57BL/6 F1 mice using recombinant hIL-6 as the immunizing antigen |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-6 is 0, Western blot: To detect hIL-6 by Western Blot analysis this antibody can be used at a concentration of 0, a concentration of 4, under reducing or non-reducing conditions, #956, 0 ug/mL, 0 ug/mL of this antibody will detect at least 500 pg/mL of recombinant human IL-6 when used with our biotinylated antigen affinity purified anti-human IL-6 (XP-5193Bt) as the detection antibody at a concentration of approximately 0, 0-8, 20-0, 25-0, 40 ug/mL, 5-1, 50 ng/lane, ELISA: In a sandwich ELISA (assuming 100 &, L/well) |
| Keep at: |
Reconstitute in sterile water to a concentration of 0, The antibody is stable for at least six weeks at 2-4 grades C when reconstituted, 0 mg/mL, 1 - 1, IL-6 lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20 grades C |
| Works with: |
Human |
| Omim nr: |
124347 |
| Ncbi nr: |
P05231 |
| Vial with antibody: |
Lyophilized |
| NCBI GENE nr: |
3569 |
| GENE symbol: |
IL6 |
| Antigene name: |
beta 2), interleukin 6 (interferon |
| Source: |
Homo sapiens |
| Protein nr: |
P05231 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
2-2B11-2G10], IL-6 [1 |
| Short name: |
2-2B11-2G10], anti-IL-6 Antibody [1 |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
2-2B11-2G10], antibody to-Interleukin-6 (Antibody to) [1 |
| Alternative technique: |
antibodies |
| Identity: |
6018 |
| Gene: |
IL6 |
More about : IL6 |
| Long gene name: |
interleukin 6 |
| Synonyms gene: |
IFNB2 |
| Synonyms gene name: |
beta 2) , interleukin 6 (interferon |
| Synonyms: |
IL-6 BSF2 HGF HSF |
| Synonyms name: |
beta 2 , interferon |
| Locus: |
7p15, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M18403 |
| Entrez gene record: |
3569 |
| Pubmed identfication: |
3294161 |
| RefSeq identity: |
NM_000600 |
| Classification: |
Interleukins Interferons Interleukin 6 cytokine family |
| Havana BLAST/BLAT: |
OTTHUMG00000023178 |