| Alternative name 1: |
Clone: 4G2-2A6, Mab anti-, ERCC2 |
| Alternative name 2: |
Clone: 4G2-2A6, Mab antibody-, ERCC2 |
| Alternative name 3: |
Clone: 4G2-2A6, Mab antibody-, ERCC2 |
| Alternative name 4: |
anti-ERCC2 Clone: 4G2-2A6 |
| Alternative name 5: |
ERCC2 Clone: 4G2-2A6 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4G2-2A6, ERCC2 |
| Short name: |
Mouse Monoclonal antibody- Clone: 4G2-2A6, ERCC2 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4G2-2A6, complementation family 2, excision repair cross-complementing rodent repair deficiency |
| Alternative technique: |
murine |
| Alternative to gene target: |
4 sulfur cluster binding, 4 sulfur cluster binding, 4 sulfur cluster binding and molecular function this GO :0060218 and hematopoietic stem cell differentiation and biological process this GO :0071817 and MMXD complex and cellular component this GO :1901990 and regulation of mitotic cell cycle phase transition and biological process, COFS2 and EM9 and TFIIH and TTD and XPD, DNA damage removal and biological process this GO :0001666 and response to hypoxia and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0004003 and ATP-dependent DNA helicase activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005675 and holo TFIIH complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0006139 and nucleobase-containing compound metabolic process and biological process this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006360 and transcription from RNA polymerase I promoter and biological process this GO :0006361 and transcription initiation from RNA polymerase I promoter and biological process this GO :0006362 and transcription elongation from RNA polymerase I promoter and biological process this GO :0006363 and termination of RNA polymerase I transcription and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0006368 and transcription elongation from RNA polymerase II promoter and biological process this GO :0006370 and 7-methylguanosine mRNA capping and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007059 and chromosome segregation and biological process this GO :0007568 and aging and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008026 and ATP-dependent helicase activity and molecular function this GO :0008094 and DNA-dependent ATPase activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008353 and RNA polymerase II carboxy-terminal domain kinase activity and molecular function this GO :0009411 and response to UV and biological process this GO :0009650 and UV protection and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010467 and gene expression and biological process this GO :0016032 and viral process and biological process this GO :0016818 and hydrolase activity, DNA incision and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0035315 and hair cell differentiation and biological process this GO :0040016 and embryonic cleavage and biological process this GO :0043139 and 5'-3' DNA helicase activity and molecular function this GO :0043249 and erythrocyte maturation and biological process this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043588 and skin development and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048820 and hair follicle maturation and biological process this GO :0050434 and positive regulation of viral transcription and biological process this GO :0051539 and 4 iron, ERCC2 and IDBG-57385 and ENSG00000104884 and 2068, ERCC2 and IDBG-639452 and ENSBTAG00000002072 and 100125238, Ercc2 and IDBG-150400 and ENSMUSG00000030400 and 13871, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides, complementation group 2, hydrolase activity, in phosphorus-containing anhydrides, in phosphorus-containing anhydrides and also this GO :0043139 : 5'-3' DNA helicase activity and also this GO :0046872 : metal ion binding and also this GO :0047485 : protein N-terminus binding and also this GO :0051539 : 4 iron, in phosphorus-containing anhydrides and molecular function this GO :0019907 and cyclin-dependent protein kinase activating kinase holoenzyme complex and cellular component this GO :0021510 and spinal cord development and biological process this GO :0022405 and hair cycle process and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030282 and bone mineralization and biological process this GO :0032289 and central nervous system myelin formation and biological process this GO :0032508 and DNA duplex unwinding and biological process this GO :0033683 and nucleotide-excision repair, nuclei, this GO :0000439 and core TFIIH complex and cellular component this GO :0000718 and nucleotide-excision repair, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0004003 : ATP-dependent DNA helicase activity and also this GO :0004672 : protein kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008022 : protein C-terminus binding and also this GO :0008026 : ATP-dependent helicase activity and also this GO :0008094 : DNA-dependent ATPase activity and also this GO :0008353 : RNA polymerase II carboxy-terminal domain kinase activity and also this GO :0016818 : hydrolase activity, this GO :0003677 : DNA binding, this GO :0004003 : ATP-dependent DNA helicase activity, this GO :0004672 : protein kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008022 : protein C-terminus binding, this GO :0008026 : ATP-dependent helicase activity, this GO :0008094 : DNA-dependent ATPase activity, this GO :0008353 : RNA polymerase II carboxy-terminal domain kinase activity, this GO :0016818 : hydrolase activity, this GO :0043139 : 5'-3' DNA helicase activity, this GO :0046872 : metal ion binding, this GO :0047485 : protein N-terminus binding, this GO :0051539 : 4 iron, excision repair cross-complementing rodent repair deficiency |
| Identity: |
3434 |
| Gene: |
ERCC2 |
More about : ERCC2 |
| Long gene name: |
ERCC excision repair 2, TFIIH core complex helicase subunit |
| Synonyms gene: |
XPD |
| Synonyms gene name: |
complementation group 2 excision repair cross-complementation group 2 , xeroderma pigmentosum complementary group D excision repair cross-complementing rodent repair deficiency |
| Synonyms: |
MAG EM9 MGC102762 MGC126218 MGC126219 TFIIH |
| Synonyms name: |
complementation group 2 protein TFIIH basal transcription factor complex helicase XPB subunit , excision repair cross-complementing rodent repair deficiency |
| Locus: |
19q13, 32 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2068 |
| Pubmed identfication: |
8413672 2184031 |
| RefSeq identity: |
NM_000400 |
| Classification: |
Xeroderma pigmentosum complementation groups General transcription factors ERCC excision repair associated DNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000048190 |
| Locus Specific Databases: |
The Globin Gene Server LRG_461 |