| Also known as: |
human, LIF |
| Other names: |
D factor, D factor, Differentiation-stimulating factor, INN: Emfilermin, Leukemia inhibitory factor, MLPLI, Melanoma-derived LPL inhibitor, cholinergic differentiation factor, differentiation inhibitory activity, differentiation-inducing factor, differentiation-stimulating factor, hepatocyte-stimulating factor III, human interleukin in DA cells, leukemia inhibitory factor, leukemia inhibitory factor, melanoma-derived LPL inhibitor, leukemia inhibitory factor isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
LIF |
| Other gene names: |
CDF, D factor, DIA, HILDA, HILDA, LIF, LIF, MLPLI, MLPLI, LIF |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Form/Appearance: |
Protein G Purified-Liquid |
| Storage and shipping: |
Frozen |
| Tested applications:: |
Western Blot (WB) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal, LIF |
| Short name: |
Monoclonal Antibody, Mouse, human, LIF |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Species: |
Mouses, Mouse |
| Alternative name: |
H, Mouse, monoclonal (Antibody to), sapiens, leukemia inhibitory factor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CDF and DIA and HILDA and MLPLI, Extracellular, LIF and IDBG-3968 and ENSG00000128342 and 3976, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, growth factor activity, this GO :0001135 and RNA polymerase II transcription factor recruiting transcription factor activity and molecular function this GO :0001974 and blood vessel remodeling and biological process this GO :0005102 and receptor binding and molecular function this GO :0005125 and cytokine activity and molecular function this GO :0005146 and leukemia inhibitory factor receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006955 and immune response and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007566 and embryo implantation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0030324 and lung development and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033141 and positive regulation of peptidyl-serine phosphorylation of STAT protein and biological process this GO :0042503 and tyrosine phosphorylation of Stat3 protein and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045835 and negative regulation of meiosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046697 and decidualization and biological process this GO :0046888 and negative regulation of hormone secretion and biological process this GO :0048286 and lung alveolus development and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048861 and leukemia inhibitory factor signaling pathway and biological process this GO :0048863 and stem cell differentiation and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0060135 and maternal process involved in female pregnancy and biological process this GO :0060426 and lung vasculature development and biological process this GO :0060463 and lung lobe morphogenesis and biological process this GO :0060707 and trophoblast giant cell differentiation and biological process this GO :0060708 and spongiotrophoblast differentiation and biological process this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0072108 and positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0072307 and regulation of metanephric nephron tubule epithelial cell differentiation and biological process this GO :1900182 and positive regulation of protein localization to nucleus and biological process this GO :1901676 and positive regulation of histone H3-K27 acetylation and biological process, this GO :0001135 : RNA polymerase II transcription factor recruiting transcription factor activity, this GO :0001135 : RNA polymerase II transcription factor recruiting transcription factor activity and also this GO :0005102 : receptor binding and also this GO :0005125 : cytokine activity and also this GO :0005146 : leukemia inhibitory factor receptor binding and also this GO :0008083 : growth factor activity, this GO :0005102 : receptor binding, this GO :0005125 : cytokine activity, this GO :0005146 : leukemia inhibitory factor receptor binding, this GO :0008083 : growth factor activity, leukemia inhibitory factor |
| Identity: |
6596 |
| Gene: |
LIF |
More about : LIF |
| Long gene name: |
leukemia inhibitory factor |
| Synonyms: |
CDF DIA HILDA |
| Synonyms name: |
differentiation inhibitory activity differentiation-inducing factor hepatocyte-stimulating factor III cholinergic differentiation factor human interleukin in DA cells |
| Locus: |
22q12, 2 |
| Discovery year: |
1989-06-11 |
| Entrez gene record: |
3976 |
| Pubmed identfication: |
1714745 8058719 |
| RefSeq identity: |
NM_002309 |
| Classification: |
Endogenous ligands Interleukin 6 cytokine family |
| Havana BLAST/BLAT: |
OTTHUMG00000150910 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |