| Also known as: |
HDAC2 |
| Other names: |
Histone deacetylase 2, N/A, YY1-associated factor 1, histone deacetylase 2, histone deacetylase 2, transcriptional regulator homolog RPD3, histone deacetylase 2 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
HDAC2 |
| Other gene names: |
HD2, HD2, HDAC2, RPD3, YAF1, HDAC2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
3F3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Cow, Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens) Predicted to work with: Chicken, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Purification method: |
Protein G |
| Form/Appearance: |
1% sodium azide, Purified antibody (from supernatant) containing PBS + 0 |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol has to added and the vial must be stored at -20°, C, Lyophilized antibodies may be transported at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage |
| Tested applications:: |
Chromatin Immunoprecipitation (ChIP), IHC-P, Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
HDAC2 [3F3] |
| Short name: |
Mouse Anti-HDAC2 [3F3] |
| Technique: |
mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse antibody to-histone deacetylase 2 [3F3] |
| Alternative technique: |
murine |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006476 and protein deacetylation and biological process this GO :0007596 and blood coagulation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009913 and epidermal cell differentiation and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0010977 and negative regulation of neuron projection development and biological process this GO :0016358 and dendrite development and biological process this GO :0016575 and histone deacetylation and biological process this GO :0016580 and Sin3 complex and cellular component this GO :0016581 and NuRD complex and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019213 and deacetylase activity and molecular function this GO :0019899 and enzyme binding and molecular function this GO :0021766 and hippocampus development and biological process this GO :0030182 and neuron differentiation and biological process this GO :0031072 and heat shock protein binding and molecular function this GO :0031490 and chromatin DNA binding and molecular function this GO :0031492 and nucleosomal DNA binding and molecular function this GO :0032041 and NAD-dependent histone deacetylase activity (H3-K14 specific) and molecular function this GO :0032922 and circadian regulation of gene expression and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033558 and protein deacetylase activity and molecular function this GO :0034605 and cellular response to heat and biological process this GO :0035098 and ESC/E(Z) complex and cellular component this GO :0035851 and Krueppel-associated box domain binding and molecular function this GO :0042220 and response to cocaine and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042493 and response to drug and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0043044 and ATP-dependent chromatin remodeling and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045347 and negative regulation of MHC class II biosynthetic process and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046969 and NAD-dependent histone deacetylase activity (H3-K9 specific) and molecular function this GO :0046970 and NAD-dependent histone deacetylase activity (H4-K16 specific) and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051896 and regulation of protein kinase B signaling and biological process this GO :0055013 and cardiac muscle cell development and biological process this GO :0060044 and negative regulation of cardiac muscle cell proliferation and biological process this GO :0060297 and regulation of sarcomere organization and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0061029 and eyelid development in camera-type eye and biological process this GO :0061198 and fungiform papilla formation and biological process this GO :0070932 and histone H3 deacetylation and biological process this GO :0070933 and histone H4 deacetylation and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090311 and regulation of protein deacetylation and biological process this GO :0097372 and NAD-dependent histone deacetylase activity (H3-K18 specific) and molecular function this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, HD2 and RPD3 and YAF1, HDAC2 and IDBG-631217 and ENSBTAG00000011849 and 407223, HDAC2 and IDBG-95591 and ENSG00000196591 and 3066, Hdac2 and IDBG-143980 and ENSMUSG00000019777 and 15182, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000785 and chromatin and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000792 and heterochromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001047 and core promoter binding and molecular function this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004407 and histone deacetylase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005657 and replication fork and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006344 and maintenance of chromatin silencing and biological process this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001047 : core promoter binding and also this GO :0001103 : RNA polymerase II repressing transcription factor binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004407 : histone deacetylase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0019213 : deacetylase activity and also this GO :0019899 : enzyme binding and also this GO :0031072 : heat shock protein binding and also this GO :0031490 : chromatin DNA binding and also this GO :0031492 : nucleosomal DNA binding and also this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific) and also this GO :0033558 : protein deacetylase activity and also this GO :0035851 : Krueppel-associated box domain binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific) and also this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific) and also this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), this GO :0000980 : RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0001047 : core promoter binding, this GO :0001103 : RNA polymerase II repressing transcription factor binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0004407 : histone deacetylase activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0019213 : deacetylase activity, this GO :0019899 : enzyme binding, this GO :0031072 : heat shock protein binding, this GO :0031490 : chromatin DNA binding, this GO :0031492 : nucleosomal DNA binding, this GO :0032041 : NAD-dependent histone deacetylase activity (H3-K14 specific), this GO :0033558 : protein deacetylase activity, this GO :0035851 : Krueppel-associated box domain binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044822 : poly(A) RNA binding, this GO :0046969 : NAD-dependent histone deacetylase activity (H3-K9 specific), this GO :0046970 : NAD-dependent histone deacetylase activity (H4-K16 specific), this GO :0097372 : NAD-dependent histone deacetylase activity (H3-K18 specific), histone deacetylase 2 |
| Identity: |
4853 |
| Gene: |
HDAC2 |
More about : HDAC2 |
| Long gene name: |
histone deacetylase 2 |
| Synonyms: |
RPD3 YAF1 |
| Locus: |
6q21 |
| Discovery year: |
1996-11-15 |
| GenBank acession: |
U31814 |
| Entrez gene record: |
3066 |
| Pubmed identfication: |
9782097 |
| Classification: |
NuRD complex Histone deacetylases, class I EMSY complex SIN3 histone deacetylase complex |
| Havana BLAST/BLAT: |
OTTHUMG00000015411 |