| Also known as: |
CD226 |
| Other names: |
CD226 antigen, CD226 antigen, CD226 molecule, DNAX accessory molecule 1, DNAX accessory molecule 1, DNAX accessory molecule-1, T lineage-specific activation antigen 1 antigen, adhesion glycoprotein, platelet and T cell activation antigen 1, CD226 antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD226 |
| Other gene names: |
CD226, DNAM-1, DNAM-1, DNAM1, DNAM1, PTA1, TLiSA1, CD226 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
DX11 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD226 is also expressed by a subset of CD3 positive thymocytes, CD226 is broadly expressed on T-cells, Clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells, NK cells, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, a 65kD glycoprotein, also known as DNAM1 (DNAX accessory molecule-1), monocytes and a subset of B cells, platelets, CD226 Recognises human CD226 |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0 mg/ml, IgG concentration 1 |
| Storage and shipping: |
If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use, Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided, Shelf Life: 18 months from date of dispatch, Storage in frost-free freezers is not recommended, the antibody should be stored undiluted, Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term |
| Tested applications:: |
Immunoprecipitation (IP), Flow Cytometry (FACS) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD226 |
| Short name: |
MOUSE Anti-HUMAN CD226 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens CD226 molecule (Antibody to), MOUSE antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD226 and IDBG-4779 and ENSG00000150637 and 10666, CD226 and IDBG-643547 and ENSBTAG00000009266 and 615496, Cd226 and IDBG-163478 and ENSMUSG00000034028 and 225825, Cell surfaces, DNAM-1 and DNAM1 and PTA1 and TLiSA1, cell adhesion molecule binding, this GO :0001816 and cytokine production and biological process this GO :0002860 and positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target and biological process this GO :0002891 and positive regulation of immunoglobulin mediated immune response and biological process this GO :0005178 and integrin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0008037 and cell recognition and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0033005 and positive regulation of mast cell activation and biological process this GO :0045121 and membrane raft and cellular component this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0060369 and positive regulation of Fc receptor mediated stimulatory signaling pathway and biological process, this GO :0005178 : integrin binding, this GO :0005178 : integrin binding and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0050839 : cell adhesion molecule binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0050839 : cell adhesion molecule binding, CD226 molecule |
| Identity: |
16961 |
| Gene: |
CD226 |
More about : CD226 |
| Long gene name: |
CD226 molecule |
| Synonyms gene name: |
CD226 antigen |
| Synonyms: |
DNAM-1 DNAM1 PTA1 TLiSA1 |
| Locus: |
18q22, 2 |
| Discovery year: |
2003-10-02 |
| GenBank acession: |
U56102 |
| Entrez gene record: |
10666 |
| Pubmed identfication: |
8673704 |
| RefSeq identity: |
NM_006566 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132809 |